SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		5 / 12 ILE A 350
PHE A 394
THR A 386
LEU A 420
ILE A 349
 None
 1.10A 1cd2A-5dn7A:
undetectable		 1cd2A-5dn7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		4 / 6 LEU A 414
VAL A 442
VAL A 435
SER A 439
 None
 0.95A 1e7aB-5dn7A:
undetectable		 1e7aB-5dn7A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		4 / 4 THR A 413
LEU A 417
LEU A 424
GLN A 427
 None
 1.07A 1fbmA-5dn7A:
undetectable		 1fbmA-5dn7A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		4 / 6 THR A 386
GLN A 427
LEU A 420
LEU A 424
 None
 0.98A 3bgdA-5dn7A:
undetectable		 3bgdA-5dn7A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		4 / 5 LEU A 354
GLN A 376
LEU A 374
GLU A 373
 None
 1.09A 3h5gA-5dn7A:
undetectable
3h5gB-5dn7A:
undetectable		 3h5gA-5dn7A:
8.57
3h5gB-5dn7A:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		5 / 9 LEU A 461
GLY A 433
VAL A 428
VAL A 421
LEU A 420
 None
 1.22A 4qd3A-5dn7A:
undetectable		 4qd3A-5dn7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		5 / 12 GLY A 393
ILE A 395
PHE A 394
THR A 386
LEU A 417
 None
 1.39A 5nz0A-5dn7A:
undetectable		 5nz0A-5dn7A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		4 / 8 THR A 413
GLY A 412
LEU A 374
ALA A 370
 None
 0.71A 5vw5A-5dn7A:
undetectable		 5vw5A-5dn7A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		5 / 12 LEU A 572
VAL A 489
LEU A 471
GLY A 541
LEU A 548
 None
 1.09A 6a7pA-5dn7A:
2.8		 6a7pA-5dn7A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		3 / 3 ARG A 524
LYS A 451
ARG A 523
 None
 1.45A 6az3C-5dn7A:
undetectable
6az3L-5dn7A:
undetectable
6az3M-5dn7A:
undetectable		 6az3C-5dn7A:
14.43
6az3L-5dn7A:
13.41
6az3M-5dn7A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 5dn7 PROTEIN FAM179B
(Mus
musculus) 		4 / 5 VAL A 564
LEU A 530
VAL A 490
LEU A 536
 None
 0.97A 6bqgA-5dn7A:
undetectable		 6bqgA-5dn7A:
13.99