SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dni PUTATIVE
L(+)-TARTRATE
DEHYDRATASE SUBUNIT
BETA
(Methanocaldococc
us
jannaschii) 		4 / 7 GLY A  78
HIS A  60
THR A  80
THR A  30
 GOL  A 201 (-3.4A)
None
None
None
 0.86A 1c9sT-5dniA:
undetectable
1c9sU-5dniA:
undetectable		 1c9sT-5dniA:
19.89
1c9sU-5dniA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dni PUTATIVE
L(+)-TARTRATE
DEHYDRATASE SUBUNIT
BETA
(Methanocaldococc
us
jannaschii) 		4 / 7 GLY A  78
HIS A  60
THR A  80
THR A  30
 GOL  A 201 (-3.4A)
None
None
None
 0.87A 1gtfL-5dniA:
undetectable
1gtfM-5dniA:
undetectable		 1gtfL-5dniA:
19.89
1gtfM-5dniA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dni PUTATIVE
L(+)-TARTRATE
DEHYDRATASE SUBUNIT
BETA
(Methanocaldococc
us
jannaschii) 		4 / 8 GLY A  78
HIS A  60
THR A  80
THR A  30
 GOL  A 201 (-3.4A)
None
None
None
 0.88A 1gtfN-5dniA:
undetectable
1gtfO-5dniA:
undetectable		 1gtfN-5dniA:
19.89
1gtfO-5dniA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 5dni PUTATIVE
L(+)-TARTRATE
DEHYDRATASE SUBUNIT
BETA
(Methanocaldococc
us
jannaschii) 		4 / 4 GLY A 105
SER A  82
ILE A 101
HIS A  60
 GOL  A 202 (-4.8A)
None
None
None
 1.31A 1yajJ-5dniA:
undetectable		 1yajJ-5dniA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 5dni PUTATIVE
L(+)-TARTRATE
DEHYDRATASE SUBUNIT
BETA
(Methanocaldococc
us
jannaschii) 		4 / 4 GLY A 106
SER A  82
ILE A 101
HIS A  60
 GOL  A 202 (-3.5A)
None
None
None
 1.23A 1yajJ-5dniA:
undetectable		 1yajJ-5dniA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5dni PUTATIVE
L(+)-TARTRATE
DEHYDRATASE SUBUNIT
BETA
(Methanocaldococc
us
jannaschii) 		3 / 3 HIS A  60
HIS A  36
ILE A  58
 None
 0.86A 3u52A-5dniA:
undetectable
3u52C-5dniA:
undetectable		 3u52A-5dniA:
16.17
3u52C-5dniA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 5dni PUTATIVE
L(+)-TARTRATE
DEHYDRATASE SUBUNIT
BETA
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  57
TYR A  59
LEU A  24
LEU A 123
ILE A  21
 None
 1.06A 4g1bD-5dniA:
undetectable		 4g1bD-5dniA:
21.17