SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dnl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5dnl IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
(Pyrococcus
furiosus) 		3 / 3 GLU A 149
HIS A 145
HIS A  29
 None
 0.31A 1oe2A-5dnlA:
undetectable		 1oe2A-5dnlA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 5dnl IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
(Pyrococcus
furiosus) 		5 / 11 LEU A 119
ALA A  87
VAL A 123
LEU A 126
LEU A 155
 None
 1.07A 1rlbF-5dnlA:
undetectable		 1rlbF-5dnlA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5dnl IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
(Pyrococcus
furiosus) 		5 / 12 LEU A  27
ALA A  33
LEU A 155
LEU A  62
THR A  22
 None
 1.27A 1ya3B-5dnlA:
undetectable		 1ya3B-5dnlA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5dnl IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
(Pyrococcus
furiosus) 		5 / 12 LEU A  27
ALA A  33
LEU A 155
LEU A  62
THR A  22
 None
 1.29A 2oaxC-5dnlA:
undetectable		 2oaxC-5dnlA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 5dnl IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
(Pyrococcus
furiosus) 		5 / 12 LEU A 126
LEU A 159
ILE A  14
GLU A  68
PHE A  34
 None
 1.18A 2weyA-5dnlA:
undetectable		 2weyA-5dnlA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5dnl IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
(Pyrococcus
furiosus) 		5 / 12 LEU A  27
ALA A  33
LEU A 155
LEU A  62
THR A  22
 None
 1.33A 3vhuA-5dnlA:
undetectable		 3vhuA-5dnlA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 5dnl IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
(Pyrococcus
furiosus) 		5 / 11 GLY A  63
ALA A  65
ILE A  14
LEU A  31
ILE A  44
 None
 0.98A 4dt8A-5dnlA:
undetectable		 4dt8A-5dnlA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 5dnl IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
(Pyrococcus
furiosus) 		5 / 10 ASP A  94
VAL A  93
GLY A 129
ILE A  60
ILE A 134
 None
 1.12A 4q1wB-5dnlA:
undetectable		 4q1wB-5dnlA:
20.00