SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5do2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	5do2	4C2 HEAVY CHAIN (Mus musculus)	4 / 4	THR H 120 PRO H 150 THR H 119 PRO H 121	None	1.33A	1dsdC-5do2H: undetectable	1dsdC-5do2H: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	5do2	4C2 HEAVY CHAIN (Mus musculus)	4 / 4	THR H 120 PRO H 150 THR H 119 PRO H 121	None	1.33A	1dsdC-5do2H: undetectable	1dsdC-5do2H: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_A_8MOA501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	5do2	4C2 HEAVY CHAIN (Mus musculus)	6 / 11	PHE H 29 ASN H 74 GLY H 55 THR H 58 ILE H 70 LEU H 79	None	1.33A	1z11A-5do2H: undetectable	1z11A-5do2H: 19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y03_B_5FWB601_1 (BETA-1 ADRENERGIC RECEPTOR)	5do2	4C2 HEAVY CHAIN (Mus musculus)	5 / 12	VAL H 166 VAL H 184 SER H 182 ASN H 199 ASN H 158	None	1.49A	2y03B-5do2H: undetectable	2y03B-5do2H: 20.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6CJK_B_ACTB302_0 (IMMUNOGLOBULIN FAB HEAVY CHAIN)	5do2	4C2 HEAVY CHAIN (Mus musculus)	3 / 3	TYR H 60 GLY H 66 THR H 69	None	0.13A	6cjkB-5do2H: 25.5	6cjkB-5do2H: 58.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","5do2","4C2 HEAVY CHAIN","Mus musculus",4,"THR H 120;PRO H 150;THR H 119;PRO H 121","None","1.33A","1dsdC-5do2H:undetectable","1dsdC-5do2H:13.33"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","5do2","4C2 HEAVY CHAIN","Mus musculus",4,"THR H 120;PRO H 150;THR H 119;PRO H 121","None","1.33A","1dsdC-5do2H:undetectable","1dsdC-5do2H:13.33"],["1Z11_A_8MOA501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","5do2","4C2 HEAVY CHAIN","Mus musculus",6,"PHE H  29;ASN H  74;GLY H  55;THR H  58;ILE H  70;LEU H  79","None","1.33A","1z11A-5do2H:undetectable","1z11A-5do2H:19.15"],["2Y03_B_5FWB601_1","BETA-1 ADRENERGIC RECEPTOR","5do2","4C2 HEAVY CHAIN","Mus musculus",5,"VAL H 166;VAL H 184;SER H 182;ASN H 199;ASN H 158","None","1.49A","2y03B-5do2H:undetectable","2y03B-5do2H:20.44"],["6CJK_B_ACTB302_0","IMMUNOGLOBULIN FAB HEAVY CHAIN","5do2","4C2 HEAVY CHAIN","Mus musculus",3,"TYR H  60;GLY H  66;THR H  69","None","0.13A","6cjkB-5do2H:25.5","6cjkB-5do2H:58.74"]]