SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2I30_A_SALA1200_1 (SERUM ALBUMIN)	5dok	TELOMERASE ASSOCIATED PROTEIN P45 (Tetrahymena thermophila)	4 / 4	LEU A 275 ILE A 236 ILE A 262 ALA A 263	None	0.85A	2i30A-5dokA: undetectable	2i30A-5dokA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z90_F_4LEF401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5dok	TELOMERASE ASSOCIATED PROTEIN P45 (Tetrahymena thermophila)	4 / 8	LEU A 189 THR A 245 LEU A 246 LEU A 242	None	0.66A	4z90F-5dokA: undetectable 4z90G-5dokA: undetectable 4z90H-5dokA: undetectable 4z90I-5dokA: undetectable 4z90J-5dokA: undetectable	4z90F-5dokA: 22.37 4z90G-5dokA: 22.37 4z90H-5dokA: 22.37 4z90I-5dokA: 22.37 4z90J-5dokA: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_B_FK5B201_1 (FK506-BINDING PROTEIN 1)	5dok	TELOMERASE ASSOCIATED PROTEIN P45 (Tetrahymena thermophila)	5 / 11	ASP A 239 ARG A 191 TYR A 258 ILE A 262 ILE A 236	None MG A 401 (-4.7A) None None None	1.17A	5hw8B-5dokA: undetectable	5hw8B-5dokA: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB308_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	5dok	TELOMERASE ASSOCIATED PROTEIN P45 (Tetrahymena thermophila)	3 / 3	LEU A 242 ILE A 192 TYR A 287	None	0.66A	5uunB-5dokA: undetectable	5uunB-5dokA: 23.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2I30_A_SALA1200_1","SERUM ALBUMIN","5dok","TELOMERASE ASSOCIATED PROTEIN P45","Tetrahymena thermophila",4,"LEU A 275;ILE A 236;ILE A 262;ALA A 263","None","0.85A","2i30A-5dokA:undetectable","2i30A-5dokA:14.92"],["4Z90_F_4LEF401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1;GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1;GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1;GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1;GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","5dok","TELOMERASE ASSOCIATED PROTEIN P45","Tetrahymena thermophila",4,"LEU A 189;THR A 245;LEU A 246;LEU A 242","None","0.66A","4z90F-5dokA:undetectable;4z90G-5dokA:undetectable;4z90H-5dokA:undetectable;4z90I-5dokA:undetectable;4z90J-5dokA:undetectable","4z90F-5dokA:22.37;4z90G-5dokA:22.37;4z90H-5dokA:22.37;4z90I-5dokA:22.37;4z90J-5dokA:22.37"],["5HW8_B_FK5B201_1","FK506-BINDING PROTEIN 1","5dok","TELOMERASE ASSOCIATED PROTEIN P45","Tetrahymena thermophila",5,"ASP A 239;ARG A 191;TYR A 258;ILE A 262;ILE A 236","None; MG A 401 (-4.7A);None;None;None","1.17A","5hw8B-5dokA:undetectable","5hw8B-5dokA:22.56"],["5UUN_B_ACTB308_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","5dok","TELOMERASE ASSOCIATED PROTEIN P45","Tetrahymena thermophila",3,"LEU A 242;ILE A 192;TYR A 287","None","0.66A","5uunB-5dokA:undetectable","5uunB-5dokA:23.42"]]