SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dp1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_C_SPMC921_1
(FMS1 PROTEIN)		 5dp1 CURK
(Moorea
producens) 		5 / 11 ASN A 228
LEU A  55
LYS A 324
PHE A  45
LEU A  49
 None
 1.48A 1xpqC-5dp1A:
0.7		 1xpqC-5dp1A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 5dp1 CURK
(Moorea
producens) 		5 / 12 GLY A 249
ASN A 228
LEU A 227
ASP A 272
GLY A 142
 None
 0.98A 2f8lA-5dp1A:
8.0		 2f8lA-5dp1A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 5dp1 CURK
(Moorea
producens) 		6 / 12 GLY A 165
GLY A 163
ALA A 159
THR A 182
ALA A 181
ALA A 168
 None
GOL  A 403 ( 3.7A)
None
None
None
None
 1.31A 2gluB-5dp1A:
8.8		 2gluB-5dp1A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5dp1 CURK
(Moorea
producens) 		5 / 11 HIS A 325
GLU A 230
GLY A 229
ILE A 232
VAL A 223
 None
 1.25A 2uxpB-5dp1A:
undetectable		 2uxpB-5dp1A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5dp1 CURK
(Moorea
producens) 		5 / 12 LEU A 227
ASN A 225
GLY A 249
VAL A 223
PHE A 245
 None
 1.40A 3gn8B-5dp1A:
undetectable		 3gn8B-5dp1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5dp1 CURK
(Moorea
producens) 		5 / 12 ALA A 181
LEU A 194
LEU A 191
SER A 202
ILE A 179
 None
 1.39A 3lbdA-5dp1A:
undetectable		 3lbdA-5dp1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 5dp1 CURK
(Moorea
producens) 		5 / 12 PHE A 271
LEU A 224
VAL A 155
ALA A 172
ALA A 139
 None
 1.23A 4fiaA-5dp1A:
undetectable		 4fiaA-5dp1A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5dp1 CURK
(Moorea
producens) 		5 / 12 PHE A 271
LEU A 224
VAL A 155
ALA A 172
ALA A 139
 None
 1.23A 4fiaA-5dp1A:
undetectable		 4fiaA-5dp1A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5dp1 CURK
(Moorea
producens) 		4 / 7 GLY A 252
ILE A 232
ASN A 225
GLU A 247
 None
 1.06A 4g0vA-5dp1A:
2.4		 4g0vA-5dp1A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5dp1 CURK
(Moorea
producens) 		4 / 7 ASP A 104
GLN A   7
LYS A   9
TYR A  59
 None
 1.34A 6g31G-5dp1A:
undetectable		 6g31G-5dp1A:
13.37