SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dps'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_B_SAMB602_1 (HYPOTHETICAL PROTEIN)	5dps	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1,GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN (Homo sapiens)	3 / 3	GLU A 24 ASP A 109 TYR A 113	None	0.75A	2yvlB-5dpsA: undetectable	2yvlB-5dpsA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z85_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5dps	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1,GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN (Homo sapiens)	4 / 6	GLN A 66 PHE A 67 PHE A 85 LEU A 83	None	1.12A	5z85P-5dpsA: undetectable 5z85W-5dpsA: undetectable	5z85P-5dpsA: 17.74 5z85W-5dpsA: 17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5dps	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1,GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN (Homo sapiens)	4 / 6	GLN A 66 PHE A 67 PHE A 85 LEU A 83	None	1.09A	5z86C-5dpsA: undetectable 5z86J-5dpsA: undetectable	5z86C-5dpsA: 17.74 5z86J-5dpsA: 17.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YVL_B_SAMB602_1","HYPOTHETICAL PROTEIN","5dps","PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1,GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN","Homo sapiens",3,"GLU A  24;ASP A 109;TYR A 113","None","0.75A","2yvlB-5dpsA:undetectable","2yvlB-5dpsA:21.95"],["5Z85_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5dps","PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1,GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN","Homo sapiens",4,"GLN A  66;PHE A  67;PHE A  85;LEU A  83","None","1.12A","5z85P-5dpsA:undetectable;5z85W-5dpsA:undetectable","5z85P-5dpsA:17.74;5z85W-5dpsA:17.76"],["5Z86_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5dps","PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1,GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN","Homo sapiens",4,"GLN A  66;PHE A  67;PHE A  85;LEU A  83","None","1.09A","5z86C-5dpsA:undetectable;5z86J-5dpsA:undetectable","5z86C-5dpsA:17.74;5z86J-5dpsA:17.76"]]