SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		5 / 12 ASN A 665
LEU A 663
MET A 629
THR A 297
ILE A 300
 None
 1.15A 1p93A-5dqqA:
undetectable		 1p93A-5dqqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		4 / 6 PHE A 137
LEU A  70
ILE A  66
SER A 140
 None
 1.23A 1sbrA-5dqqA:
undetectable
1sbrB-5dqqA:
undetectable		 1sbrA-5dqqA:
14.47
1sbrB-5dqqA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		4 / 8 PHE A 368
ILE A 348
PHE A 372
ILE A 334
 None
 0.98A 2qwxA-5dqqA:
undetectable
2qwxB-5dqqA:
undetectable		 2qwxA-5dqqA:
15.33
2qwxB-5dqqA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		5 / 12 THR A 485
TYR A 486
GLY A 495
ARG A 543
ILE A 436
 None
 1.11A 3ijdA-5dqqA:
undetectable		 3ijdA-5dqqA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		4 / 6 PHE A 284
ILE A 233
ALA A 230
THR A 254
 None
 1.12A 3mdrA-5dqqA:
undetectable		 3mdrA-5dqqA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		4 / 5 VAL A 575
PHE A  86
PHE A  83
PHE A  87
 None
 1.00A 3owxB-5dqqA:
undetectable		 3owxB-5dqqA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		5 / 9 GLY A 619
VAL A 621
PRO A 617
PRO A  97
GLY A 110
 None
 1.34A 4fimA-5dqqA:
undetectable		 4fimA-5dqqA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		4 / 8 PHE A 368
ILE A 348
PHE A 372
ILE A 334
 None
 0.97A 4qogA-5dqqA:
undetectable
4qogB-5dqqA:
undetectable		 4qogA-5dqqA:
15.33
4qogB-5dqqA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		5 / 12 LEU A 206
CYH A 574
LEU A 663
GLY A 570
SER A 210
 None
 1.45A 4zbrA-5dqqA:
undetectable		 4zbrA-5dqqA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		3 / 3 GLY A 487
ASN A 490
ARG A 428
 None
 0.74A 5w7bD-5dqqA:
undetectable		 5w7bD-5dqqA:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5dqq TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Arabidopsis
thaliana) 		3 / 3 LYS A 156
LEU A 152
ARG A 203
 None
 0.91A 5yw0A-5dqqA:
undetectable		 5yw0A-5dqqA:
18.44