SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dqr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ASN A 307
ASN A 234
ILE A 314
GLY A 315
 None
FAD  A 503 (-4.6A)
FAD  A 503 (-4.7A)
FAD  A 503 (-3.5A)
 1.02A 1oniA-5dqrA:
undetectable
1oniB-5dqrA:
undetectable		 1oniA-5dqrA:
17.95
1oniB-5dqrA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ASN A 307
ASN A 234
ILE A 314
GLY A 315
 None
FAD  A 503 (-4.6A)
FAD  A 503 (-4.7A)
FAD  A 503 (-3.5A)
 1.01A 1oniD-5dqrA:
undetectable
1oniF-5dqrA:
undetectable		 1oniD-5dqrA:
17.95
1oniF-5dqrA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 LEU A 231
LEU A 205
LEU A 225
MET A 344
 None
 1.06A 2oaxF-5dqrA:
undetectable		 2oaxF-5dqrA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1314_1
(CHOLINE-BINDING
PROTEIN F)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 LYS A 103
ASP A 109
ARG A 102
GLU A  94
 None
 1.05A 2x8oA-5dqrA:
undetectable		 2x8oA-5dqrA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 PHE A 247
LEU A 186
GLY A 239
GLY A 243
ASP A 293
 None
 1.08A 2zbpA-5dqrA:
undetectable		 2zbpA-5dqrA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 VAL A 319
PRO A 320
PRO A 331
ILE A 135
ILE A 354
 None
None
None
FAD  A 503 (-4.4A)
None
 1.33A 3ganA-5dqrA:
undetectable		 3ganA-5dqrA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 PHE A 247
PHE A 263
TYR A 261
VAL A 294
 None
 1.15A 3lb3A-5dqrA:
undetectable		 3lb3A-5dqrA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 PHE A 247
PHE A 263
TYR A 261
VAL A 294
 None
 1.18A 3lb3B-5dqrA:
undetectable		 3lb3B-5dqrA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 TYR A 305
GLY A 315
ILE A 334
PHE A 112
LEU A 407
 FAD  A 503 (-4.6A)
FAD  A 503 (-3.5A)
None
None
None
 1.35A 4kovA-5dqrA:
undetectable		 4kovA-5dqrA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 286
GLU A 280
VAL A 281
HIS A 417
SER A 413
 None
 1.30A 4ydqA-5dqrA:
undetectable		 4ydqA-5dqrA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 ILE A 135
LEU A 352
ILE A 334
LEU A 312
 FAD  A 503 (-4.4A)
None
None
None
 0.74A 4zvcA-5dqrA:
undetectable
4zvcB-5dqrA:
undetectable		 4zvcA-5dqrA:
15.51
4zvcB-5dqrA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 ILE A 334
LEU A 312
ILE A 135
LEU A 352
 None
None
FAD  A 503 (-4.4A)
None
 0.74A 4zvcA-5dqrA:
undetectable
4zvcB-5dqrA:
undetectable		 4zvcA-5dqrA:
15.51
4zvcB-5dqrA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 THR A 110
ASP A 415
GLU A 408
 None
 0.77A 5fa8A-5dqrA:
undetectable		 5fa8A-5dqrA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP A 105
ALA A 104
THR A 306
THR A 418
SER A 106
 None
 1.39A 5hfjH-5dqrA:
undetectable		 5hfjH-5dqrA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 291
VAL A 294
GLY A 243
PHE A 263
VAL A 269
 None
 1.45A 6a94A-5dqrA:
undetectable		 6a94A-5dqrA:
19.15