SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_B_ACTB1424_0 (FPRA)	5dr5	ABD09097 FAB HEAVY CHAIN (Homo sapiens)	4 / 4	ALA H 92 ARG H 38 GLN H 39 GLU H 46	None	1.45A	1lquB-5dr5H: undetectable	1lquB-5dr5H: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_B_8MOB501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	5dr5	ABD09097 FAB HEAVY CHAIN (Homo sapiens)	6 / 11	PHE H 29 ASN H 74 GLY H 55 THR H 58 ILE H 70 LEU H 79	None	1.47A	1z11B-5dr5H: undetectable	1z11B-5dr5H: 19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5dr5	ABD09097 FAB HEAVY CHAIN (Homo sapiens)	4 / 7	ALA H 92 THR H 91 VAL H 111 GLU H 89	None	0.72A	5ecmD-5dr5H: undetectable	5ecmD-5dr5H: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5dr5	ABD09097 FAB HEAVY CHAIN (Homo sapiens)	4 / 7	ALA H 92 THR H 91 VAL H 111 GLU H 89	None	0.82A	5ecoD-5dr5H: undetectable	5ecoD-5dr5H: 19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6CJK_B_ACTB302_0 (IMMUNOGLOBULIN FAB HEAVY CHAIN)	5dr5	ABD09097 FAB HEAVY CHAIN (Homo sapiens)	3 / 3	TYR H 60 GLY H 66 THR H 69	None	0.16A	6cjkB-5dr5H: 24.3	6cjkB-5dr5H: 58.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LQU_B_ACTB1424_0","FPRA","5dr5","ABD09097 FAB HEAVY CHAIN","Homo sapiens",4,"ALA H  92;ARG H  38;GLN H  39;GLU H  46","None","1.45A","1lquB-5dr5H:undetectable","1lquB-5dr5H:19.14"],["1Z11_B_8MOB501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","5dr5","ABD09097 FAB HEAVY CHAIN","Homo sapiens",6,"PHE H  29;ASN H  74;GLY H  55;THR H  58;ILE H  70;LEU H  79","None","1.47A","1z11B-5dr5H:undetectable","1z11B-5dr5H:19.42"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5dr5","ABD09097 FAB HEAVY CHAIN","Homo sapiens",4,"ALA H  92;THR H  91;VAL H 111;GLU H  89","None","0.72A","5ecmD-5dr5H:undetectable","5ecmD-5dr5H:19.53"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5dr5","ABD09097 FAB HEAVY CHAIN","Homo sapiens",4,"ALA H  92;THR H  91;VAL H 111;GLU H  89","None","0.82A","5ecoD-5dr5H:undetectable","5ecoD-5dr5H:19.53"],["6CJK_B_ACTB302_0","IMMUNOGLOBULIN FAB HEAVY CHAIN","5dr5","ABD09097 FAB HEAVY CHAIN","Homo sapiens",3,"TYR H  60;GLY H  66;THR H  69","None","0.16A","6cjkB-5dr5H:24.3","6cjkB-5dr5H:58.33"]]