SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5drn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_B_ADNB438_2 (ADENOSYLHOMOCYSTEINA SE)	5drn	FAB HPU24 HEAVY CHAIN (Oryctolagus cuniculus)	3 / 3	THR A 87 GLU A 148 HIS A 197	None	0.77A	3g1uB-5drnA: undetectable	3g1uB-5drnA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_C_ADNC500_2 (ADENOSYLHOMOCYSTEINA SE)	5drn	FAB HPU24 HEAVY CHAIN (Oryctolagus cuniculus)	4 / 5	LEU A 108 GLN A 39 THR A 89 GLU A 148	None	1.16A	3n58C-5drnA: undetectable	3n58C-5drnA: 20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SU9_A_ACTA426_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5drn	FAB HPU24 HEAVY CHAIN (Oryctolagus cuniculus)	3 / 3	GLN A 3 GLU A 2 LYS A 2	PCA A 1 ( 4.5A) None PCA A 1 ( 3.2A)	1.19A	3su9A-5drnA: undetectable	3su9A-5drnA: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I6X_A_8PRA705_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	5drn	FAB HPU24 HEAVY CHAIN (Oryctolagus cuniculus)	5 / 10	ALA A 93 ILE A 35 GLY A 52 GLY A 95 VAL A 76	None	1.13A	5i6xA-5drnA: undetectable	5i6xA-5drnA: 18.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3G1U_B_ADNB438_2","ADENOSYLHOMOCYSTEINASE","5drn","FAB HPU24 HEAVY CHAIN","Oryctolagus cuniculus",3,"THR A  87;GLU A 148;HIS A 197","None","0.77A","3g1uB-5drnA:undetectable","3g1uB-5drnA:19.05"],["3N58_C_ADNC500_2","ADENOSYLHOMOCYSTEINASE","5drn","FAB HPU24 HEAVY CHAIN","Oryctolagus cuniculus",4,"LEU A 108;GLN A  39;THR A  89;GLU A 148","None","1.16A","3n58C-5drnA:undetectable","3n58C-5drnA:20.14"],["3SU9_A_ACTA426_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","5drn","FAB HPU24 HEAVY CHAIN","Oryctolagus cuniculus",3,"GLN A   3;GLU A   2;LYS A   2","PCA A   1 ( 4.5A);None;PCA A   1 ( 3.2A)","1.19A","3su9A-5drnA:undetectable","3su9A-5drnA:21.31"],["5I6X_A_8PRA705_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","5drn","FAB HPU24 HEAVY CHAIN","Oryctolagus cuniculus",5,"ALA A  93;ILE A  35;GLY A  52;GLY A  95;VAL A  76","None","1.13A","5i6xA-5drnA:undetectable","5i6xA-5drnA:18.03"]]