SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5drv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5drv RAS
GTPASE-ACTIVATING
PROTEIN-BINDING
PROTEIN 2
(Homo
sapiens) 		3 / 3 TYR A  20
TYR A  40
GLN A 110
 None
 1.12A 5jsdA-5drvA:
undetectable
5jsdB-5drvA:
undetectable		 5jsdA-5drvA:
10.89
5jsdB-5drvA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5drv RAS
GTPASE-ACTIVATING
PROTEIN-BINDING
PROTEIN 2
(Homo
sapiens) 		3 / 3 TYR A  20
TYR A  40
GLN A 110
 None
 1.13A 5jsdB-5drvA:
undetectable
5jsdC-5drvA:
undetectable		 5jsdB-5drvA:
10.89
5jsdC-5drvA:
10.89