SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ds8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ds8 FAB HPU98 HEAVY
CHAIN
(Oryctolagus
cuniculus) 		3 / 3 THR A  87
GLU A 148
HIS A 197
 EDO  A 303 (-4.6A)
EDO  A 303 (-3.6A)
None
 0.82A 3g1uB-5ds8A:
undetectable		 3g1uB-5ds8A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5ds8 FAB HPU98 HEAVY
CHAIN
(Oryctolagus
cuniculus) 		3 / 3 SER A  96
ASP A 101
ASP A  98
 None
 0.89A 3iv6A-5ds8A:
undetectable		 3iv6A-5ds8A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5ds8 FAB HPU98 HEAVY
CHAIN
(Oryctolagus
cuniculus) 		3 / 3 SER A  96
ASP A 101
ASP A  98
 None
 0.87A 3iv6C-5ds8A:
undetectable		 3iv6C-5ds8A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ds8 FAB HPU98 HEAVY
CHAIN
(Oryctolagus
cuniculus) 		4 / 5 LEU A 108
GLN A  39
THR A  89
GLU A 148
 EDO  A 303 ( 4.7A)
None
None
EDO  A 303 (-3.6A)
 1.26A 3n58C-5ds8A:
undetectable		 3n58C-5ds8A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5ds8 FAB HPU98 HEAVY
CHAIN
(Oryctolagus
cuniculus) 		4 / 7 ALA A  88
THR A  87
VAL A 109
GLU A  85
 None
EDO  A 303 (-4.6A)
None
None
 0.84A 5ecoD-5ds8A:
undetectable		 5ecoD-5ds8A:
17.86