SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dss'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 5dss MP-4
(Mucuna
pruriens) 		5 / 12 ALA B 181
GLY B 182
GLY B 183
ILE B  23
GLY B 177
 None
 1.03A 1sqfA-5dssB:
undetectable		 1sqfA-5dssB:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 5dss MP-4
(Mucuna
pruriens) 		4 / 5 TYR B  53
PRO B  25
THR B  40
THR B  48
 None
 1.43A 1ymxB-5dssB:
undetectable		 1ymxB-5dssB:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 5dss MP-4
(Mucuna
pruriens) 		4 / 6 LEU B 174
VAL B 176
VAL B 155
PHE B  64
 None
 1.09A 3soaA-5dssB:
undetectable		 3soaA-5dssB:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5dss MP-4
(Mucuna
pruriens) 		4 / 7 GLY B 101
GLY B 120
TYR B 158
ALA B 108
 None
 1.01A 5e26A-5dssB:
undetectable
5e26B-5dssB:
undetectable		 5e26A-5dssB:
20.83
5e26B-5dssB:
20.83