SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dtc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5dtc RIBOSOME BIOGENESIS
PROTEIN YTM1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  42
PHE A  12
ARG A  36
LEU A  68
 None
 0.91A 2eijN-5dtcA:
undetectable
2eijW-5dtcA:
undetectable		 2eijN-5dtcA:
9.94
2eijW-5dtcA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5dtc RIBOSOME BIOGENESIS
PROTEIN YTM1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  42
PHE A  12
ARG A  36
LEU A  68
 None
 0.91A 2eikN-5dtcA:
undetectable
2eikW-5dtcA:
undetectable		 2eikN-5dtcA:
9.94
2eikW-5dtcA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5dtc RIBOSOME BIOGENESIS
PROTEIN YTM1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  42
PHE A  12
ARG A  36
LEU A  68
 None
 0.90A 2eilN-5dtcA:
undetectable
2eilW-5dtcA:
undetectable		 2eilN-5dtcA:
9.94
2eilW-5dtcA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5dtc RIBOSOME BIOGENESIS
PROTEIN YTM1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  42
PHE A  12
ARG A  36
LEU A  68
 None
 0.91A 3asnN-5dtcA:
undetectable
3asnW-5dtcA:
undetectable		 3asnN-5dtcA:
9.94
3asnW-5dtcA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 5dtc RIBOSOME BIOGENESIS
PROTEIN YTM1
(Saccharomyces
cerevisiae) 		5 / 10 LEU A  83
ILE A  42
GLY A  38
VAL A   8
ILE A  10
 None
 0.97A 3em3B-5dtcA:
undetectable		 3em3B-5dtcA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5dtc RIBOSOME BIOGENESIS
PROTEIN YTM1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  42
PHE A  12
ARG A  36
LEU A  68
 None
 0.90A 5iy5N-5dtcA:
undetectable
5iy5W-5dtcA:
undetectable		 5iy5N-5dtcA:
9.94
5iy5W-5dtcA:
28.57