SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dth'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5dth MULTIPLE PDZ DOMAIN
PROTEIN
(Rattus
norvegicus) 		4 / 6 THR A1330
ILE A1392
TYR A1394
THR A1332
 None
 0.94A 3q70A-5dthA:
undetectable		 3q70A-5dthA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 5dth MULTIPLE PDZ DOMAIN
PROTEIN
(Rattus
norvegicus) 		4 / 8 ILE A1392
GLU A1387
TYR A1328
LEU A1331
 None
 1.05A 3rqwI-5dthA:
undetectable
3rqwJ-5dthA:
undetectable		 3rqwI-5dthA:
14.29
3rqwJ-5dthA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 5dth MULTIPLE PDZ DOMAIN
PROTEIN
(Rattus
norvegicus) 		3 / 3 GLN A1334
HIS A1336
ARG A1418
 None
 1.23A 4qyqA-5dthA:
undetectable		 4qyqA-5dthA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 5dth MULTIPLE PDZ DOMAIN
PROTEIN
(Rattus
norvegicus) 		3 / 3 GLN A1334
HIS A1336
ARG A1418
 None
 1.19A 4qyqB-5dthA:
undetectable		 4qyqB-5dthA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 5dth MULTIPLE PDZ DOMAIN
PROTEIN
(Rattus
norvegicus) 		5 / 12 LEU A1385
GLY A1374
ILE A1388
ALA A1408
GLY A1371
 None
 0.91A 5veuH-5dthA:
undetectable		 5veuH-5dthA:
12.90