SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5du2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		4 / 8 LEU A 294
ALA A 297
VAL A 232
VAL A 263
 None
 0.78A 1epbB-5du2A:
undetectable		 1epbB-5du2A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		4 / 5 TYR A  45
GLU A  44
TYR A  59
PRO A  58
 None
 1.22A 1mclA-5du2A:
undetectable
1mclB-5du2A:
undetectable
1mclP-5du2A:
undetectable		 1mclA-5du2A:
18.85
1mclB-5du2A:
18.85
1mclP-5du2A:
0.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		5 / 11 ARG A  33
VAL A 210
GLY A 382
ALA A 208
LEU A 189
 None
 1.20A 2bxgA-5du2A:
undetectable		 2bxgA-5du2A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		5 / 9 LEU A 290
VAL A 301
THR A 302
ALA A 308
LEU A 294
 None
 1.19A 2m9qA-5du2A:
undetectable		 2m9qA-5du2A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		3 / 3 PRO A 125
GLU A 398
TYR A 394
 None
 0.60A 2zmbA-5du2A:
undetectable		 2zmbA-5du2A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		5 / 10 GLU A 356
ARG A 353
GLY A 351
CYH A 251
MET A 264
 None
 1.43A 3adsA-5du2A:
undetectable		 3adsA-5du2A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		5 / 9 ARG A 212
ILE A 192
LEU A 340
THR A 302
GLY A 316
 None
 1.19A 3nxuB-5du2A:
undetectable		 3nxuB-5du2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		4 / 6 PHE A 196
ILE A 192
ARG A 212
VAL A 328
 None
 1.25A 4mk4B-5du2A:
4.3		 4mk4B-5du2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		4 / 5 LEU A 164
ASP A 161
TYR A  82
LEU A  83
 None
 1.25A 4wozF-5du2A:
undetectable
4wozH-5du2A:
undetectable		 4wozF-5du2A:
22.09
4wozH-5du2A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5du2 ESPG2
GLYCOSYLTRANSFERASE
(Actinomadura
verrucosospora) 		5 / 12 LEU A  30
LEU A  11
PRO A 131
ILE A 129
ARG A 212
 None
 1.39A 5uahC-5du2A:
undetectable		 5uahC-5du2A:
15.79