SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dub'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5dub FAB HPU98 LIGHT
CHAIN
(Oryctolagus
cuniculus) 		3 / 3 GLN B 154
THR B 153
THR B 152
 None
 0.67A 4fu9A-5dubB:
undetectable		 4fu9A-5dubB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5dub FAB HPU98 LIGHT
CHAIN
(Oryctolagus
cuniculus) 		3 / 3 GLN B 154
THR B 153
THR B 152
 None
 0.67A 4fufA-5dubB:
undetectable		 4fufA-5dubB:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 5dub FAB HPU98 LIGHT
CHAIN
(Oryctolagus
cuniculus) 		4 / 4 VAL B  15
GLY B 108
ASP B 109
ASP B 169
 None
 0.36A 6cjkC-5dubB:
28.3		 6cjkC-5dubB:
87.56