SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dum'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 95 MET H 93 THR H 121 LEU H 122	None	1.42A	2eimJ-5dumH: undetectable	2eimJ-5dumH: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 95 MET H 93 THR H 121 LEU H 122	None	1.40A	2eimW-5dumH: undetectable	2eimW-5dumH: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 95 MET H 93 THR H 121 LEU H 122	None	1.40A	3ag2J-5dumH: undetectable	3ag2J-5dumH: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 95 MET H 93 THR H 121 LEU H 122	None	1.40A	3ag4J-5dumH: undetectable	3ag4J-5dumH: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EIG_A_MTXA200_2 (DIHYDROFOLATE REDUCTASE)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	4 / 5	ASP H 55 ARG H 50 ILE H 58 VAL H 79	None	0.93A	3eigA-5dumH: undetectable	3eigA-5dumH: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JX1_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	5 / 10	PHE H 136 GLY H 132 THR H 219 VAL H 212 VAL H 221	None	1.15A	4jx1B-5dumH: undetectable	4jx1B-5dumH: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_E_DVAE7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	3 / 3	TYR H 57 SER H 56 TRP H 33	None	1.06A	5n8jB-5dumH: undetectable	5n8jB-5dumH: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_O_DVAO7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	3 / 3	TYR H 57 SER H 56 TRP H 33	None	1.02A	5n8jA-5dumH: undetectable	5n8jA-5dumH: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_P_DVAP5_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	3 / 3	TYR H 57 SER H 56 TRP H 33	None	1.04A	5n8jD-5dumH: undetectable	5n8jD-5dumH: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5dum	65C6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 95 MET H 93 THR H 121 LEU H 122	None	1.40A	5z86J-5dumH: undetectable	5z86J-5dumH: 11.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2EIM_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","5dum","65C6 HEAVY CHAIN","Homo sapiens",4,"TYR H  95;MET H  93;THR H 121;LEU H 122","None","1.42A","2eimJ-5dumH:undetectable","2eimJ-5dumH:11.86"],["2EIM_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","5dum","65C6 HEAVY CHAIN","Homo sapiens",4,"TYR H  95;MET H  93;THR H 121;LEU H 122","None","1.40A","2eimW-5dumH:undetectable","2eimW-5dumH:11.86"],["3AG2_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","5dum","65C6 HEAVY CHAIN","Homo sapiens",4,"TYR H  95;MET H  93;THR H 121;LEU H 122","None","1.40A","3ag2J-5dumH:undetectable","3ag2J-5dumH:11.86"],["3AG4_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","5dum","65C6 HEAVY CHAIN","Homo sapiens",4,"TYR H  95;MET H  93;THR H 121;LEU H 122","None","1.40A","3ag4J-5dumH:undetectable","3ag4J-5dumH:11.86"],["3EIG_A_MTXA200_2","DIHYDROFOLATE REDUCTASE","5dum","65C6 HEAVY CHAIN","Homo sapiens",4,"ASP H  55;ARG H  50;ILE H  58;VAL H  79","None","0.93A","3eigA-5dumH:undetectable","3eigA-5dumH:19.75"],["4JX1_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","5dum","65C6 HEAVY CHAIN","Homo sapiens",5,"PHE H 136;GLY H 132;THR H 219;VAL H 212;VAL H 221","None","1.15A","4jx1B-5dumH:undetectable","4jx1B-5dumH:18.31"],["5N8J_E_DVAE7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","5dum","65C6 HEAVY CHAIN","Homo sapiens",3,"TYR H  57;SER H  56;TRP H  33","None","1.06A","5n8jB-5dumH:undetectable","5n8jB-5dumH:24.18"],["5N8J_O_DVAO7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","5dum","65C6 HEAVY CHAIN","Homo sapiens",3,"TYR H  57;SER H  56;TRP H  33","None","1.02A","5n8jA-5dumH:undetectable","5n8jA-5dumH:24.18"],["5N8J_P_DVAP5_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","5dum","65C6 HEAVY CHAIN","Homo sapiens",3,"TYR H  57;SER H  56;TRP H  33","None","1.04A","5n8jD-5dumH:undetectable","5n8jD-5dumH:24.18"],["5Z86_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5dum","65C6 HEAVY CHAIN","Homo sapiens",4,"TYR H  95;MET H  93;THR H 121;LEU H 122","None","1.40A","5z86J-5dumH:undetectable","5z86J-5dumH:11.86"]]