SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5dur HEAVY CHAIN OF
ANTIBODY 100F4
(Homo
sapiens) 		5 / 12 VAL H 171
VAL H 190
SER H 188
ASN H 205
ASN H 163
 None
 1.40A 2y03A-5durH:
undetectable		 2y03A-5durH:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5dur HEAVY CHAIN OF
ANTIBODY 100F4
(Homo
sapiens) 		5 / 12 VAL H 171
VAL H 190
SER H 188
ASN H 205
ASN H 163
 None
 1.45A 2y03B-5durH:
undetectable		 2y03B-5durH:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 5dur HEAVY CHAIN OF
ANTIBODY 100F4
(Homo
sapiens) 		5 / 11 TYR H 153
HIS H 208
LEU H 116
ALA H 176
THR H  92
 None
 1.21A 3jwqB-5durH:
undetectable
3jwqC-5durH:
undetectable		 3jwqB-5durH:
18.34
3jwqC-5durH:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5dur HEAVY CHAIN OF
ANTIBODY 100F4
(Homo
sapiens) 		5 / 12 VAL H 171
VAL H 190
SER H 188
ASN H 205
ASN H 163
 None
 1.38A 3nyaA-5durH:
undetectable		 3nyaA-5durH:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5dur HEAVY CHAIN OF
ANTIBODY 100F4
(Homo
sapiens) 		5 / 10 PHE H 130
GLY H 126
THR H 213
VAL H 206
VAL H 215
 None
 1.20A 4jx1B-5durH:
undetectable		 4jx1B-5durH:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 5dur HEAVY CHAIN OF
ANTIBODY 100F4
(Homo
sapiens) 		5 / 10 VAL H 171
VAL H 190
SER H 188
ASN H 205
ASN H 163
 None
 1.49A 4ldoA-5durH:
undetectable		 4ldoA-5durH:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5dur HEAVY CHAIN OF
ANTIBODY 100F4
(Homo
sapiens) 		5 / 12 VAL H 171
VAL H 190
SER H 188
ASN H 205
ASN H 163
 None
 1.44A 6h7mB-5durH:
undetectable		 6h7mB-5durH:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5dur HEAVY CHAIN OF
ANTIBODY 100F4
(Homo
sapiens) 		5 / 11 GLY H  51
LEU H  39
ALA H  98
ALA H 100
PHE H 108
 None
 1.20A 6qgbA-5durH:
undetectable		 6qgbA-5durH:
17.52