SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		3 / 3 THR A 272
PRO A   8
PRO A 271
 None
 0.87A 2d55C-5dv5A:
undetectable		 2d55C-5dv5A:
2.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		5 / 12 LEU A 188
PHE A 189
LEU A 192
SER A 124
VAL A 251
 None
 1.27A 2pnjB-5dv5A:
undetectable		 2pnjB-5dv5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		5 / 12 LEU A 188
PHE A 189
LEU A 192
SER A 124
VAL A 251
 None
 1.05A 3aqiB-5dv5A:
undetectable		 3aqiB-5dv5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		5 / 10 PHE A  25
SER A  19
LEU A  48
VAL A  43
VAL A  51
 None
 1.40A 3u9fE-5dv5A:
undetectable		 3u9fE-5dv5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		5 / 9 PHE A  25
SER A  19
LEU A  48
VAL A  43
VAL A  51
 None
 1.41A 3u9fP-5dv5A:
undetectable		 3u9fP-5dv5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		5 / 12 LEU A 188
PHE A 189
LEU A 192
SER A 124
VAL A 251
 None
 1.03A 3w1wA-5dv5A:
undetectable		 3w1wA-5dv5A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		4 / 5 LEU A  86
ALA A  94
ASN A  93
ILE A  17
 None
 1.09A 4y03B-5dv5A:
undetectable		 4y03B-5dv5A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E2I_A_DMEA605_1
(ACETYLCHOLINESTERASE)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		4 / 6 ASP A 185
TYR A 219
PHE A 232
TYR A 233
 PKZ  A 301 ( 4.3A)
PKZ  A 301 (-3.7A)
None
None
 1.47A 5e2iA-5dv5A:
undetectable		 5e2iA-5dv5A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		5 / 12 ALA A   9
ILE A  20
TYR A  15
ILE A  41
LEU A  61
 None
 1.03A 5h8tA-5dv5A:
undetectable		 5h8tA-5dv5A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_C_PFLC407_1
(PROTON-GATED ION
CHANNEL)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		5 / 9 TYR A 184
ILE A 148
VAL A 157
THR A 180
ILE A 177
 PKZ  A 302 (-4.1A)
None
PKZ  A 302 ( 4.2A)
None
None
 1.40A 5mvnC-5dv5A:
undetectable		 5mvnC-5dv5A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 5dv5 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Vibrio
alginolyticus) 		5 / 10 TYR A 184
ILE A 148
VAL A 157
THR A 180
ILE A 177
 PKZ  A 302 (-4.1A)
None
PKZ  A 302 ( 4.2A)
None
None
 1.40A 5mvnD-5dv5A:
undetectable		 5mvnD-5dv5A:
17.41