SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5dvh PCPI-3
(Solanum
tuberosum) 		3 / 3 LYS A  66
SER A  73
GLN A  76
 None
 1.27A 3si7A-5dvhA:
undetectable		 3si7A-5dvhA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5dvh PCPI-3
(Solanum
tuberosum) 		4 / 4 ASN A 193
ILE A  80
TYR A  63
PHE A  71
 None
 1.49A 5igvA-5dvhA:
undetectable		 5igvA-5dvhA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5dvh PCPI-3
(Solanum
tuberosum) 		4 / 8 LEU A 178
VAL A 115
VAL A  46
ILE A  80
 None
 0.70A 5y9mX-5dvhA:
undetectable		 5y9mX-5dvhA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 5dvh PCPI-3
(Solanum
tuberosum) 		5 / 12 TYR A 150
VAL A 115
ARG A 149
VAL A 167
ASP A 166
 None
 1.37A 6bxlB-5dvhA:
undetectable		 6bxlB-5dvhA:
18.77