SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dvj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		4 / 4 GLY A  66
ASP A 249
GLY A 188
THR A 195
 None
 0.58A 1hxbB-5dvjA:
undetectable		 1hxbB-5dvjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 10 GLY A  68
LEU A 385
GLN A 388
ASN A 380
GLY A  67
 GAL  A 501 (-3.5A)
None
None
None
GAL  A 501 (-3.3A)
 1.43A 1kvlA-5dvjA:
undetectable		 1kvlA-5dvjA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		3 / 3 MET A 129
ASN A 141
GLN A 332
 None
 1.01A 1xoqB-5dvjA:
undetectable		 1xoqB-5dvjA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLY A 279
ALA A 278
GLY A  39
GLY A  40
ILE A 258
 None
 0.70A 2avsA-5dvjA:
undetectable		 2avsA-5dvjA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLY A 279
ALA A 278
GLY A  39
GLY A  40
ILE A 258
 None
 0.62A 2avvA-5dvjA:
undetectable		 2avvA-5dvjA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLY A 279
ALA A 278
GLY A  39
GLY A  40
ILE A 258
 None
 0.71A 2avvD-5dvjA:
undetectable		 2avvD-5dvjA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 ILE A 391
MET A 264
PHE A 155
ALA A 160
ALA A 171
 None
 1.35A 2x2nD-5dvjA:
undetectable		 2x2nD-5dvjA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLY A 279
ALA A 278
GLY A  39
GLY A  40
ILE A 258
 None
 0.73A 3cyxB-5dvjA:
undetectable		 3cyxB-5dvjA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLY A 279
ALA A 278
GLY A  39
VAL A 257
ILE A 258
 None
 0.95A 3cyxB-5dvjA:
undetectable		 3cyxB-5dvjA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLY A 279
ALA A 278
GLY A  40
VAL A 257
ILE A 258
 None
 0.93A 3cyxB-5dvjA:
undetectable		 3cyxB-5dvjA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		4 / 4 GLY A  66
ASP A 249
GLY A 188
THR A 195
 None
 0.57A 3k4vC-5dvjA:
undetectable		 3k4vC-5dvjA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 ASP A 303
ILE A 128
PHE A 298
ASP A 269
SER A 360
 GAL  A 501 (-2.8A)
None
None
None
None
 0.96A 3ko0G-5dvjA:
undetectable
3ko0H-5dvjA:
undetectable
3ko0I-5dvjA:
undetectable
3ko0J-5dvjA:
undetectable		 3ko0G-5dvjA:
11.48
3ko0H-5dvjA:
11.48
3ko0I-5dvjA:
11.48
3ko0J-5dvjA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 ILE A 266
LEU A 200
ALA A 173
LEU A 166
GLY A 263
 GOL  A 502 (-3.9A)
None
None
None
None
 1.12A 3uq6B-5dvjA:
undetectable		 3uq6B-5dvjA:
27.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 LEU A 373
PHE A 298
PRO A 122
GLN A 124
VAL A 125
 None
None
SO4  A 503 (-4.6A)
SO4  A 503 ( 4.7A)
None
 1.38A 4b3aA-5dvjA:
undetectable		 4b3aA-5dvjA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		3 / 3 GLY A  39
SER A  38
TRP A 250
 None
None
GAL  A 501 (-4.0A)
 0.92A 4e7cD-5dvjA:
undetectable		 4e7cD-5dvjA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 10 GLY A  67
GLY A  66
ASN A 301
GLN A 388
PHE A 392
 GAL  A 501 (-3.3A)
None
GAL  A 501 (-3.2A)
None
None
 0.96A 4fgkA-5dvjA:
undetectable
4fgkB-5dvjA:
undetectable		 4fgkA-5dvjA:
19.48
4fgkB-5dvjA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 11 GLN A 319
ALA A 323
ALA A 326
VAL A 344
LEU A 121
 None
 1.05A 4j6cA-5dvjA:
undetectable		 4j6cA-5dvjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 10 GLN A 319
ALA A 323
ALA A 326
VAL A 344
LEU A 121
 None
 1.04A 4j6cB-5dvjA:
undetectable		 4j6cB-5dvjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLN A 319
ALA A 323
ALA A 326
VAL A 344
LEU A 121
 None
 1.04A 4j6dA-5dvjA:
undetectable		 4j6dA-5dvjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLN A 319
ALA A 323
ALA A 326
VAL A 344
LEU A 121
 None
 1.04A 4j6dB-5dvjA:
undetectable		 4j6dB-5dvjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 GLN A 319
ALA A 323
ALA A 326
VAL A 344
LEU A 121
 None
 1.02A 4jbtA-5dvjA:
undetectable		 4jbtA-5dvjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 11 GLN A 319
ALA A 323
ALA A 326
VAL A 344
LEU A 121
 None
 1.01A 4jbtB-5dvjA:
undetectable		 4jbtB-5dvjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		4 / 5 LEU A 373
GLU A 366
LEU A 202
HIS A 211
 None
 1.00A 4xi3B-5dvjA:
undetectable		 4xi3B-5dvjA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 ILE A 266
PRO A 292
LEU A 169
GLU A 198
PHE A 291
 GOL  A 502 (-3.9A)
None
None
None
None
 1.25A 5il1A-5dvjA:
undetectable		 5il1A-5dvjA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 12 ILE A 266
PRO A 292
LEU A 169
GLU A 198
PHE A 291
 GOL  A 502 (-3.9A)
None
None
None
None
 1.32A 5k7uA-5dvjA:
undetectable		 5k7uA-5dvjA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 11 THR A  37
ALA A  65
GLY A  66
ALA A  72
LEU A 385
 None
 1.00A 5lf7H-5dvjA:
undetectable
5lf7I-5dvjA:
undetectable		 5lf7H-5dvjA:
21.48
5lf7I-5dvjA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		5 / 11 THR A  37
ALA A  65
GLY A  66
ALA A  72
LEU A 385
 None
 0.99A 5lf7V-5dvjA:
undetectable
5lf7W-5dvjA:
undetectable		 5lf7V-5dvjA:
21.48
5lf7W-5dvjA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		4 / 6 PRO A  27
GLY A  28
THR A  29
ASN A 314
 None
 1.11A 5xxiA-5dvjA:
undetectable		 5xxiA-5dvjA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dvj BINDING PROTEIN
COMPONENT OF ABC
SUGAR TRANSPORTER
(Pseudomonas
putida) 		4 / 7 TRP A 270
HIS A 379
THR A 195
HIS A  34
 GAL  A 501 (-3.6A)
GAL  A 501 (-3.9A)
None
None
 1.05A 6mn4E-5dvjA:
undetectable		 6mn4E-5dvjA:
21.67