SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dwa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		5 / 10 ALA A  50
PHE A  32
ALA A  99
LEU A 197
VAL A 199
 None
 1.17A 1claA-5dwaA:
undetectable		 1claA-5dwaA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		4 / 5 LEU A 100
PHE A 269
VAL A 143
ALA A 167
 None
 1.21A 2cizA-5dwaA:
undetectable		 2cizA-5dwaA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		3 / 3 LYS A 224
ARG A 174
VAL A 175
 None
 1.10A 2r2vC-5dwaA:
undetectable
2r2vD-5dwaA:
undetectable		 2r2vC-5dwaA:
11.82
2r2vD-5dwaA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		4 / 6 ASP A  18
ASP A  65
ASP A 208
ASN A 211
 None
 1.35A 4gkhJ-5dwaA:
undetectable		 4gkhJ-5dwaA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		3 / 3 ASN A 241
ASP A  65
ASP A 208
 None
 0.86A 4obwD-5dwaA:
undetectable		 4obwD-5dwaA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		4 / 5 TYR A  31
ILE A  28
GLY A  48
PHE A  51
 None
 0.95A 5kmdC-5dwaA:
undetectable
5kmdD-5dwaA:
undetectable		 5kmdC-5dwaA:
22.29
5kmdD-5dwaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		4 / 6 GLY A  48
PHE A  51
TYR A  31
ILE A  28
 None
 0.95A 5kmfA-5dwaA:
undetectable
5kmfC-5dwaA:
undetectable		 5kmfA-5dwaA:
22.29
5kmfC-5dwaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		5 / 12 ALA A  46
PRO A  63
TRP A  88
ALA A  50
GLY A  48
 None
 1.33A 5tzoA-5dwaA:
undetectable		 5tzoA-5dwaA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5dwa TYPE-2 RESTRICTION
ENZYME AGEI
(Thalassobius
gelatinovorus) 		5 / 12 ALA A  46
PRO A  63
TRP A  88
ALA A  50
GLY A  48
 None
 1.35A 5tzoC-5dwaA:
undetectable		 5tzoC-5dwaA:
21.68