SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dwf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 5 THR A  45
LEU A  80
GLY A  76
TYR A  82
 None
 1.23A 1gtiF-5dwfA:
undetectable		 1gtiF-5dwfA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 7 ARG A  62
VAL A  61
SER A  58
ASN A  55
 None
 1.07A 1hwiC-5dwfA:
undetectable		 1hwiC-5dwfA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 7 ARG A  62
VAL A  61
SER A  58
ASN A  55
 None
 1.06A 1hwiD-5dwfA:
undetectable		 1hwiD-5dwfA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 8 ARG A  62
VAL A  61
SER A  58
ASN A  55
 None
 1.10A 1hwkA-5dwfA:
undetectable		 1hwkA-5dwfA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 8 ARG A  62
VAL A  61
SER A  58
ASN A  55
 None
 1.12A 1hwkC-5dwfA:
undetectable		 1hwkC-5dwfA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 8 ARG A  62
VAL A  61
SER A  58
ASN A  55
 None
 1.12A 1hwkD-5dwfA:
undetectable		 1hwkD-5dwfA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 6 ASP A  44
THR A  45
PRO A  46
SER A  48
 None
 0.95A 1n4fA-5dwfA:
undetectable		 1n4fA-5dwfA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		5 / 12 TYR A 111
LEU A  80
GLY A  79
ALA A 120
LEU A 121
 None
 1.07A 4rrwC-5dwfA:
undetectable		 4rrwC-5dwfA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		5 / 12 TYR A 111
LEU A  80
GLY A  79
ALA A 120
LEU A 121
 None
 1.05A 4rrwD-5dwfA:
undetectable		 4rrwD-5dwfA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		5 / 12 TYR A 111
LEU A  80
GLY A  79
ALA A 120
LEU A 121
 None
 1.07A 4rrzC-5dwfA:
undetectable		 4rrzC-5dwfA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		5 / 12 TYR A 111
LEU A  80
GLY A  79
ALA A 120
LEU A 121
 None
 1.05A 4rrzD-5dwfA:
undetectable		 4rrzD-5dwfA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		5 / 12 LEU A 159
ASP A 148
GLY A 145
ALA A 124
TYR A 169
 None
 1.26A 5kbwB-5dwfA:
undetectable		 5kbwB-5dwfA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 4 LEU A 159
GLY A 156
SER A 154
SER A  36
 None
 1.34A 5uunA-5dwfA:
undetectable		 5uunA-5dwfA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 4 LEU A 159
GLY A 156
SER A 154
SER A  36
 None
 1.29A 5uunB-5dwfA:
undetectable		 5uunB-5dwfA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		4 / 6 ALA A  50
GLN A  54
TRP A  15
GLN A  57
 None
 1.25A 5y9aA-5dwfA:
undetectable		 5y9aA-5dwfA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1
(Camelus
dromedarius) 		5 / 12 TYR A 111
ASP A  78
LEU A  80
GLY A  79
ALA A  50
 None
 1.27A 6r2eH-5dwfA:
undetectable		 6r2eH-5dwfA:
18.35