SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 5dwu CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
(Homo
sapiens) 		3 / 3 HIS B 370
MET B 340
MET B 363
 None
 1.03A 2vj1A-5dwuB:
undetectable		 2vj1A-5dwuB:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 5dwu CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP A 116
ARG A 117
ASP B 241
 NAG  A 301 ( 4.9A)
None
None
 0.60A 4fp9D-5dwuA:
undetectable		 4fp9D-5dwuA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5dwu CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP A 116
ARG A 117
ASP B 241
 NAG  A 301 ( 4.9A)
None
None
 0.78A 4fzvA-5dwuA:
undetectable		 4fzvA-5dwuA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5dwu CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP A 116
ARG A 117
ASP B 241
 NAG  A 301 ( 4.9A)
None
None
 0.77A 5zvgA-5dwuA:
undetectable		 5zvgA-5dwuA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5dwu CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP A 116
ARG A 117
ASP B 241
 NAG  A 301 ( 4.9A)
None
None
 0.71A 5zvgB-5dwuA:
undetectable		 5zvgB-5dwuA:
18.25