SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dy1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		5 / 12 LEU A  71
VAL A  75
SER A  78
VAL A 123
HIS A 132
 None
 1.34A 1db1A-5dy1A:
undetectable		 1db1A-5dy1A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 8 LEU A 185
SER A 181
LEU A 213
ASP A 183
 None
 0.90A 2j2pA-5dy1A:
undetectable
2j2pB-5dy1A:
undetectable		 2j2pA-5dy1A:
19.68
2j2pB-5dy1A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 5 VAL A  75
THR A  74
VAL A 114
GLY A 115
 None
 0.89A 2p2fA-5dy1A:
undetectable		 2p2fA-5dy1A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 4 VAL A  75
THR A  74
VAL A 114
GLY A 115
 None
 0.94A 2p2fB-5dy1A:
undetectable		 2p2fB-5dy1A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 8 ALA A  48
ILE A  51
ILE A  45
HIS A  59
 None
 1.06A 2zmaA-5dy1A:
undetectable		 2zmaA-5dy1A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		5 / 12 THR A  79
SER A  78
LEU A 107
VAL A 166
PHE A 160
 None
 1.43A 3u9fB-5dy1A:
undetectable
3u9fC-5dy1A:
undetectable		 3u9fB-5dy1A:
20.82
3u9fC-5dy1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		5 / 12 THR A  79
SER A  78
LEU A 107
VAL A 166
PHE A 160
 None
 1.39A 3u9fH-5dy1A:
undetectable
3u9fI-5dy1A:
undetectable		 3u9fH-5dy1A:
20.82
3u9fI-5dy1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		5 / 12 PHE A 160
THR A  79
SER A  78
LEU A 107
VAL A 166
 None
 1.49A 3u9fJ-5dy1A:
undetectable
3u9fL-5dy1A:
undetectable		 3u9fJ-5dy1A:
20.82
3u9fL-5dy1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		5 / 11 THR A  79
SER A  78
LEU A 107
VAL A 166
PHE A 160
 None
 1.49A 3u9fN-5dy1A:
undetectable
3u9fO-5dy1A:
undetectable		 3u9fN-5dy1A:
20.82
3u9fO-5dy1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		5 / 12 PHE A 160
THR A  79
SER A  78
LEU A 107
VAL A 166
 None
 1.42A 3u9fP-5dy1A:
undetectable
3u9fS-5dy1A:
undetectable		 3u9fP-5dy1A:
20.82
3u9fS-5dy1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5dy1 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 5 ILE A 176
VAL A 114
LEU A  70
ASP A  26
 None
 1.19A 3wzdA-5dy1A:
undetectable		 3wzdA-5dy1A:
22.56