SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dyn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.78A 1a7yA-5dynB:
undetectable		 1a7yA-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.78A 1a7yB-5dynB:
undetectable		 1a7yB-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.82A 1a7yB-5dynB:
undetectable		 1a7yB-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.91A 1dscC-5dynB:
undetectable		 1dscC-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.85A 1fjaC-5dynB:
undetectable		 1fjaC-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.85A 1fjaD-5dynB:
undetectable		 1fjaD-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.80A 1i3wE-5dynB:
undetectable		 1i3wE-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.85A 1i3wE-5dynB:
undetectable		 1i3wE-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.77A 1i3wF-5dynB:
undetectable		 1i3wF-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.81A 1i3wG-5dynB:
undetectable		 1i3wG-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.83A 1i3wG-5dynB:
undetectable		 1i3wG-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.80A 1i3wH-5dynB:
undetectable		 1i3wH-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		4 / 6 GLY B 209
ASP B 178
TYR B 237
TRP B 252
 NA  A 403 ( 4.6A)
None
None
None
 1.22A 1kf6M-5dynB:
undetectable
1kf6N-5dynB:
undetectable		 1kf6M-5dynB:
17.92
1kf6N-5dynB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.83A 1mnvD-5dynB:
undetectable		 1mnvD-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.81A 1mnvD-5dynB:
undetectable		 1mnvD-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5dyn PUTATIVE PEPTIDASE
PUTATIVE PEPTIDASE
(Bacteroides
fragilis;
Bacteroides
fragilis) 		3 / 3 ARG A  81
ASP B 152
ASN B 154
 None
NA  A 401 (-2.3A)
None
 0.93A 1nbhA-5dynA:
undetectable		 1nbhA-5dynA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5dyn PUTATIVE PEPTIDASE
PUTATIVE PEPTIDASE
(Bacteroides
fragilis;
Bacteroides
fragilis) 		3 / 3 ARG A  81
ASP B 152
ASN B 154
 None
NA  A 401 (-2.3A)
None
 0.92A 1nbhD-5dynA:
undetectable		 1nbhD-5dynA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.80A 1ovfB-5dynB:
undetectable		 1ovfB-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.77A 1qfiA-5dynB:
undetectable		 1qfiA-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.85A 1qfiB-5dynB:
undetectable		 1qfiB-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.83A 1unjF-5dynB:
undetectable		 1unjF-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.76A 1unjF-5dynB:
undetectable		 1unjF-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.80A 1unjL-5dynB:
undetectable		 1unjL-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.76A 1unjL-5dynB:
undetectable		 1unjL-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.79A 1unjR-5dynB:
undetectable		 1unjR-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.76A 1unjR-5dynB:
undetectable		 1unjR-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.83A 1unjW-5dynB:
undetectable		 1unjW-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.77A 1unjX-5dynB:
undetectable		 1unjX-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.77A 1unjX-5dynB:
undetectable		 1unjX-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.86A 1unmE-5dynB:
undetectable		 1unmE-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.81A 1unmE-5dynB:
undetectable		 1unmE-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 282
PRO B 278
THR B 388
 None
 0.75A 1unmF-5dynB:
undetectable		 1unmF-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 THR B 388
THR B 282
PRO B 278
 None
 0.77A 1unmF-5dynB:
undetectable		 1unmF-5dynB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		5 / 12 TYR B 361
THR B 360
PRO B 363
VAL B 185
LEU B 269
 None
NA  B 402 (-3.8A)
None
None
None
 1.28A 1z9hA-5dynB:
undetectable		 1z9hA-5dynB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		5 / 12 TYR B 361
THR B 360
PRO B 363
VAL B 185
LEU B 269
 None
NA  B 402 (-3.8A)
None
None
None
 1.29A 1z9hB-5dynB:
undetectable		 1z9hB-5dynB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		5 / 12 TYR B 361
THR B 360
PRO B 363
VAL B 185
LEU B 269
 None
NA  B 402 (-3.8A)
None
None
None
 1.28A 1z9hC-5dynB:
undetectable		 1z9hC-5dynB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		4 / 7 ALA A  49
ASP A  52
ILE A  40
PRO A  80
 None
NA  A 403 (-3.1A)
None
NA  A 402 ( 4.9A)
 0.88A 2fxdB-5dynA:
undetectable		 2fxdB-5dynA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_C_SPMC503_1
(SPERMIDINE SYNTHASE)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		5 / 12 TYR B 233
ASP A  52
ASP B 178
SER B 337
TYR B 237
 None
NA  A 403 (-3.1A)
None
None
None
 1.43A 3b7pC-5dynB:
undetectable		 3b7pC-5dynB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		4 / 7 PHE A 120
LEU A  36
LEU A  82
LEU A  71
 None
 0.84A 3bgdB-5dynA:
undetectable		 3bgdB-5dynA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 TYR A  77
ASP A  75
HIS A 135
 None
NA  A 401 ( 3.0A)
None
 0.87A 3e23A-5dynA:
undetectable		 3e23A-5dynA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		4 / 8 ALA A  49
ASP A  52
ILE A  40
PRO A  80
 None
NA  A 403 (-3.1A)
None
NA  A 402 ( 4.9A)
 0.70A 3el9A-5dynA:
undetectable		 3el9A-5dynA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		4 / 8 GLU B 378
GLN B 167
ARG B 192
ASP B 193
 None
 1.13A 3mjrD-5dynB:
undetectable		 3mjrD-5dynB:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		3 / 3 TYR B 305
GLU B 204
TYR B 345
 None
 0.91A 3ug8A-5dynB:
undetectable		 3ug8A-5dynB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5dyn PUTATIVE PEPTIDASE
(Bacteroides
fragilis) 		4 / 7 GLY A 138
ILE A 140
GLU A 137
MET B 332
 None
 0.98A 4g0vA-5dynA:
undetectable		 4g0vA-5dynA:
11.23