SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dze'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		4 / 7 LEU A  78
LEU A 166
THR A  51
VAL A 207
 None
 0.95A 1dvxB-5dzeA:
undetectable		 1dvxB-5dzeA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		4 / 8 ASP A 172
VAL A 170
GLY A  43
GLY A  44
 None
 0.72A 1ekjE-5dzeA:
undetectable
1ekjF-5dzeA:
undetectable		 1ekjE-5dzeA:
18.45
1ekjF-5dzeA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		5 / 12 SER A 169
VAL A 170
GLY A  44
TYR A 175
PHE A  39
 BGC  A 302 (-2.3A)
None
None
None
None
 0.98A 1fduC-5dzeA:
undetectable		 1fduC-5dzeA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		3 / 3 GLU A  93
ASN A  73
TRP A 181
 BGC  A 305 ( 2.5A)
GLC  A 301 (-3.3A)
BGC  A 305 (-3.2A)
 1.02A 1r15C-5dzeA:
undetectable		 1r15C-5dzeA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		3 / 3 GLU A  93
ASN A  73
TRP A 181
 BGC  A 305 ( 2.5A)
GLC  A 301 (-3.3A)
BGC  A 305 (-3.2A)
 1.00A 1r15D-5dzeA:
undetectable		 1r15D-5dzeA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		3 / 3 GLU A  93
ASN A  73
TRP A 181
 BGC  A 305 ( 2.5A)
GLC  A 301 (-3.3A)
BGC  A 305 (-3.2A)
 1.03A 1r15E-5dzeA:
undetectable		 1r15E-5dzeA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		3 / 3 GLU A  93
ASN A  73
TRP A 181
 BGC  A 305 ( 2.5A)
GLC  A 301 (-3.3A)
BGC  A 305 (-3.2A)
 1.00A 1r15F-5dzeA:
undetectable		 1r15F-5dzeA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		4 / 4 ASP A  88
ASP A  91
ASP A  84
GLY A 112
 None
GLC  A 301 ( 2.8A)
None
None
 1.42A 2igtC-5dzeA:
undetectable		 2igtC-5dzeA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		4 / 6 LEU A  78
LEU A 166
SER A  49
THR A  51
 None
 1.07A 4ikiB-5dzeA:
undetectable		 4ikiB-5dzeA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		4 / 7 LEU A  78
LEU A 166
SER A  49
THR A  51
 None
 1.06A 4iklA-5dzeA:
undetectable
4iklB-5dzeA:
undetectable		 4iklA-5dzeA:
19.62
4iklB-5dzeA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IPM_A_ACTA503_0
(GH7 FAMILY PROTEIN)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		5 / 9 ASN A  73
TYR A  77
ASP A  91
GLU A  93
TRP A 171
 GLC  A 301 (-3.3A)
GLC  A 301 (-2.9A)
GLC  A 301 ( 2.8A)
BGC  A 305 ( 2.5A)
BGC  A 302 (-2.5A)
 0.70A 4ipmA-5dzeA:
12.4		 4ipmA-5dzeA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		4 / 6 TYR A 107
GLU A  82
TYR A  77
LEU A  78
 GLC  A 301 ( 3.2A)
GLC  A 301 (-2.1A)
GLC  A 301 (-2.9A)
None
 1.25A 4twdB-5dzeA:
undetectable
4twdC-5dzeA:
undetectable		 4twdB-5dzeA:
20.19
4twdC-5dzeA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		4 / 6 TYR A 107
GLU A  82
TYR A  77
LEU A  78
 GLC  A 301 ( 3.2A)
GLC  A 301 (-2.1A)
GLC  A 301 (-2.9A)
None
 1.21A 4twdD-5dzeA:
undetectable
4twdE-5dzeA:
undetectable		 4twdD-5dzeA:
20.19
4twdE-5dzeA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 5dze ENDO-GLUCANASE
(Vitis
vinifera) 		4 / 7 GLU A  82
TYR A 167
ASP A  88
ALA A  89
 GLC  A 301 (-2.1A)
None
None
GLC  A 301 ( 3.8A)
 1.03A 4zz8A-5dzeA:
4.6		 4zz8A-5dzeA:
22.80