SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dzq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 6 PRO A 162
ALA A  59
GLU A  18
GLU A  58
 None
 1.35A 1qhyA-5dzqA:
undetectable		 1qhyA-5dzqA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		3 / 3 ASP A  76
GLU A 113
TYR A 106
 None
 0.79A 1wsvA-5dzqA:
undetectable		 1wsvA-5dzqA:
21.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		5 / 7 ARG A  73
GLY A  74
SER A 118
ARG A 130
GLU A 158
 None
 1.26A 2c8aB-5dzqA:
22.6		 2c8aB-5dzqA:
36.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		5 / 7 ARG A  73
GLY A  74
SER A 118
SER A 120
ARG A 130
 None
 1.08A 2c8aB-5dzqA:
22.6		 2c8aB-5dzqA:
36.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 6 ARG A  73
SER A 118
SER A 120
ARG A 130
 None
 1.14A 2c8aC-5dzqA:
22.2		 2c8aC-5dzqA:
36.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 7 ARG A  73
GLY A  74
SER A 118
ARG A 130
 None
 0.93A 2c8aD-5dzqA:
22.6		 2c8aD-5dzqA:
36.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 7 ARG A  73
GLY A  74
SER A 118
GLU A 158
 None
 0.87A 2c8aD-5dzqA:
22.6		 2c8aD-5dzqA:
36.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 7 ARG A  73
GLY A  74
SER A 118
SER A 120
 None
 0.29A 2c8aD-5dzqA:
22.6		 2c8aD-5dzqA:
36.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		5 / 12 LEU A 136
LEU A 159
ARG A  73
SER A  63
LEU A 117
 None
 1.32A 3okxA-5dzqA:
undetectable		 3okxA-5dzqA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		5 / 12 ILE A  79
ASP A 170
ILE A 169
LEU A 136
LEU A 117
 None
GOL  A 202 (-3.4A)
None
None
None
 1.05A 4m2xE-5dzqA:
undetectable		 4m2xE-5dzqA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 8 GLU A  24
THR A 119
TYR A 116
PHE A  32
 None
 0.98A 5flcB-5dzqA:
undetectable		 5flcB-5dzqA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 8 GLU A  24
THR A 119
TYR A 116
PHE A  32
 None
 0.99A 5flcF-5dzqA:
undetectable		 5flcF-5dzqA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 7 ASN A  17
ALA A  16
GLU A  11
LEU A  21
 None
 0.88A 6ci6A-5dzqA:
undetectable		 6ci6A-5dzqA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5dzq TOXIN-LIKE PROTEIN
(Paenibacillus
larvae) 		4 / 6 LEU A 102
TYR A 106
VAL A  71
GLY A  81
 None
 0.85A 6hd4B-5dzqA:
undetectable		 6hd4B-5dzqA:
17.92