SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		3 / 3 GLU A 302
HIS A 299
HIS A 298
 None
 0.71A 1oe2A-5e0cA:
1.9		 1oe2A-5e0cA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 7 LEU A 429
GLN A 428
PHE A 427
LEU A 400
 None
 1.07A 1v55C-5e0cA:
undetectable
1v55J-5e0cA:
undetectable		 1v55C-5e0cA:
20.19
1v55J-5e0cA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		3 / 3 GLU A  34
THR A  26
LEU A  46
 None
 0.61A 1v8bC-5e0cA:
undetectable		 1v8bC-5e0cA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 9 GLY A 276
GLU A 481
ASN A 234
ILE A 284
PHE A 241
 None
 1.28A 2drdA-5e0cA:
undetectable		 2drdA-5e0cA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 8 GLY A 493
ALA A 451
THR A 440
ILE A 495
 None
 0.80A 2dtjA-5e0cA:
undetectable
2dtjB-5e0cA:
undetectable		 2dtjA-5e0cA:
16.57
2dtjB-5e0cA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 7 LEU A 429
GLN A 428
PHE A 427
LEU A 400
 None
 1.09A 2dysP-5e0cA:
undetectable
2dysW-5e0cA:
undetectable		 2dysP-5e0cA:
20.19
2dysW-5e0cA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 7 LEU A 429
GLN A 428
PHE A 427
LEU A 400
 None
 1.09A 2eimC-5e0cA:
undetectable
2eimJ-5e0cA:
undetectable		 2eimC-5e0cA:
20.19
2eimJ-5e0cA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 7 LEU A 429
GLN A 428
PHE A 427
LEU A 400
 None
 1.07A 2einC-5e0cA:
undetectable
2einJ-5e0cA:
undetectable		 2einC-5e0cA:
20.19
2einJ-5e0cA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 6 LEU A 429
GLN A 428
PHE A 427
LEU A 400
 None
 1.05A 2einP-5e0cA:
undetectable
2einW-5e0cA:
undetectable		 2einP-5e0cA:
20.19
2einW-5e0cA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		6 / 12 ASN A 148
GLU A 149
HIS A 224
TYR A 226
GLU A 271
TRP A 310
 None
 0.82A 2v3dA-5e0cA:
7.7		 2v3dA-5e0cA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 12 PHE A 272
HIS A 329
LEU A 290
ILE A 284
TYR A  55
 None
 1.47A 2xkwA-5e0cA:
undetectable		 2xkwA-5e0cA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 7 LEU A 429
GLN A 428
PHE A 427
LEU A 400
 None
 1.00A 3ag2P-5e0cA:
undetectable
3ag2W-5e0cA:
undetectable		 3ag2P-5e0cA:
20.19
3ag2W-5e0cA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 8 THR A 197
SER A 106
HIS A 103
ASN A  22
 None
 1.03A 3kp2A-5e0cA:
undetectable
3kp2B-5e0cA:
undetectable		 3kp2A-5e0cA:
14.93
3kp2B-5e0cA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		3 / 3 HIS A 298
PHE A 292
PHE A 241
 None
 0.59A 3lk0D-5e0cA:
undetectable		 3lk0D-5e0cA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NHX_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 12 TYR A 524
PHE A 482
VAL A 458
ALA A 451
PHE A 453
 None
 1.34A 3nhxA-5e0cA:
undetectable		 3nhxA-5e0cA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 12 TYR A 524
PHE A 482
VAL A 458
ALA A 451
PHE A 453
 None
 1.37A 3nuvA-5e0cA:
undetectable		 3nuvA-5e0cA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 5 PHE A 292
ILE A 249
PHE A 295
PHE A 241
 None
 1.05A 3owxB-5e0cA:
undetectable		 3owxB-5e0cA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 5 ALA A 122
GLU A 119
ALA A  71
MET A  68
 None
 1.28A 3r9tC-5e0cA:
undetectable		 3r9tC-5e0cA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		3 / 3 HIS A 103
SER A 146
GLU A 145
 None
 0.80A 3s8pA-5e0cA:
undetectable		 3s8pA-5e0cA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 7 PHE A 293
PHE A 292
GLY A 273
THR A 281
 None
 1.16A 3vnsA-5e0cA:
undetectable		 3vnsA-5e0cA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 10 ALA A 413
LEU A 429
VAL A 350
ILE A 361
ALA A 397
 None
 0.92A 4j14A-5e0cA:
undetectable		 4j14A-5e0cA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		3 / 3 HIS A 208
GLY A 264
ILE A 265
 None
 0.64A 4k50A-5e0cA:
undetectable		 4k50A-5e0cA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 4 GLY A 237
LEU A 274
PHE A 277
ILE A 284
 None
 0.96A 4xv2A-5e0cA:
undetectable		 4xv2A-5e0cA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 12 THR A 279
GLN A 474
GLY A 483
THR A 485
THR A 498
 None
 1.29A 5l66V-5e0cA:
undetectable
5l66W-5e0cA:
undetectable		 5l66V-5e0cA:
20.15
5l66W-5e0cA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		3 / 3 TRP A  64
MET A  68
ASN A  66
 None
 1.39A 5uc1A-5e0cA:
undetectable		 5uc1A-5e0cA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 12 GLU A  93
LEU A  96
ILE A  58
VAL A  42
ASP A  89
 None
 1.31A 5vlmG-5e0cA:
undetectable		 5vlmG-5e0cA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 6 TYR A 225
GLU A 271
TYR A 226
GLY A 227
 None
 0.95A 5x7pB-5e0cA:
undetectable		 5x7pB-5e0cA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 12 PHE A 272
HIS A 329
LEU A 290
ILE A 284
TYR A  55
 None
 1.42A 5ycpA-5e0cA:
undetectable		 5ycpA-5e0cA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		4 / 7 LEU A 429
GLN A 428
PHE A 427
LEU A 400
 None
 0.95A 5zcqP-5e0cA:
undetectable
5zcqW-5e0cA:
undetectable		 5zcqP-5e0cA:
20.19
5zcqW-5e0cA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5e0c CELLULASE
(Bacillus
sp.
BG-CS10) 		5 / 12 LEU A 269
GLY A 270
HIS A 224
ARG A  59
ILE A  58
 None
 1.33A 6bxnB-5e0cA:
undetectable		 6bxnB-5e0cA:
19.34