SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 7 MET A 627
ALA A 619
PHE A 726
ASN A 617
 MPD  A 802 (-4.0A)
MPD  A 802 (-3.6A)
None
MPD  A 802 (-3.5A)
 1.34A 1t9wA-5e1rA:
undetectable		 1t9wA-5e1rA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 7 TYR A 432
GLU A 476
LEU A 493
ILE A 440
 None
 1.04A 1tuvA-5e1rA:
undetectable		 1tuvA-5e1rA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 8 LEU A 712
ASN A 632
HIS A 630
ALA A 619
 MPD  A 802 ( 4.5A)
MPD  A 802 (-3.4A)
MPD  A 802 (-4.1A)
MPD  A 802 (-3.6A)
 1.00A 2bnnA-5e1rA:
10.2
2bnnB-5e1rA:
10.4		 2bnnA-5e1rA:
20.47
2bnnB-5e1rA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		3 / 3 TYR A 764
GLY A 596
PHE A 598
 None
 0.39A 2m2pB-5e1rA:
undetectable		 2m2pB-5e1rA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 8 LEU A 584
ARG A 724
VAL A 637
GLY A 716
 None
MPD  A 802 (-4.5A)
MPD  A 802 (-4.9A)
None
 1.04A 2qd5A-5e1rA:
undetectable		 2qd5A-5e1rA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		3 / 3 GLU A 405
GLN A 501
ARG A 503
 None
 0.76A 2w3bB-5e1rA:
undetectable		 2w3bB-5e1rA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 7 GLY A 714
ILE A 694
MET A 627
LEU A 712
 MPD  A 802 ( 3.8A)
None
MPD  A 802 (-4.0A)
MPD  A 802 ( 4.5A)
 0.82A 2xrhA-5e1rA:
undetectable		 2xrhA-5e1rA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 7 TYR A 399
SER A 388
ILE A 420
SER A 392
 None
 1.25A 2xz5A-5e1rA:
undetectable
2xz5B-5e1rA:
undetectable		 2xz5A-5e1rA:
18.10
2xz5B-5e1rA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 7 VAL A 638
LEU A 492
PHE A 381
LEU A 386
 None
 0.98A 3qeoB-5e1rA:
undetectable		 3qeoB-5e1rA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 7 TYR A 416
ASN A 718
ILE A 413
PHE A 403
 None
 1.27A 3tvxB-5e1rA:
undetectable		 3tvxB-5e1rA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 6 THR A 636
HIS A 698
HIS A 654
TYR A 379
 None
CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-4.3A)
 1.43A 4df2A-5e1rA:
undetectable		 4df2A-5e1rA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		3 / 3 PRO A 431
LEU A 430
GLN A 543
 None
 0.66A 4pevB-5e1rA:
undetectable		 4pevB-5e1rA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		5 / 11 LEU A 710
LEU A 712
LEU A 686
GLU A 649
ALA A 701
 None
MPD  A 802 ( 4.5A)
None
None
None
 1.02A 4wg0B-5e1rA:
undetectable
4wg0C-5e1rA:
undetectable
4wg0D-5e1rA:
undetectable		 4wg0B-5e1rA:
2.12
4wg0C-5e1rA:
2.12
4wg0D-5e1rA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		4 / 7 LEU A 517
ASN A 522
LEU A 525
LEU A 529
 None
 0.69A 4wg0B-5e1rA:
undetectable
4wg0C-5e1rA:
undetectable		 4wg0B-5e1rA:
2.12
4wg0C-5e1rA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		5 / 11 LEU A 710
LEU A 712
LEU A 686
GLU A 649
ALA A 701
 None
MPD  A 802 ( 4.5A)
None
None
None
 1.04A 4wg0F-5e1rA:
undetectable
4wg0G-5e1rA:
undetectable
4wg0H-5e1rA:
undetectable		 4wg0F-5e1rA:
2.12
4wg0G-5e1rA:
2.12
4wg0H-5e1rA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		5 / 11 LEU A 710
LEU A 712
LEU A 686
GLU A 649
ALA A 701
 None
MPD  A 802 ( 4.5A)
None
None
None
 0.85A 4wg0J-5e1rA:
undetectable
4wg0K-5e1rA:
undetectable
4wg0L-5e1rA:
undetectable		 4wg0J-5e1rA:
2.12
4wg0K-5e1rA:
2.12
4wg0L-5e1rA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		5 / 11 GLU A 649
ALA A 701
LEU A 686
LEU A 710
LEU A 712
 None
None
None
None
MPD  A 802 ( 4.5A)
 0.85A 4wg0I-5e1rA:
undetectable
4wg0J-5e1rA:
undetectable
4wg0K-5e1rA:
undetectable		 4wg0I-5e1rA:
2.12
4wg0J-5e1rA:
2.12
4wg0K-5e1rA:
2.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA501_0
(CANAVALIN)		 5e1r 7S VICILIN
(Carya
illinoinensis) 		6 / 8 ASN A 617
HIS A 630
ASN A 632
VAL A 637
ILE A 694
ARG A 724
 MPD  A 802 (-3.5A)
MPD  A 802 (-4.1A)
MPD  A 802 (-3.4A)
MPD  A 802 (-4.9A)
None
MPD  A 802 (-4.5A)
 0.26A 6cb4A-5e1rA:
43.1		 6cb4A-5e1rA:
33.83