SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e2c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 5e2c XAA-PRO DIPEPTIDASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  92
GLY A  93
ILE A  14
LEU A  23
ILE A  24
 None
 0.78A 3ijdA-5e2cA:
undetectable		 3ijdA-5e2cA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 5e2c XAA-PRO DIPEPTIDASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  92
GLY A  93
ILE A  14
LEU A  23
ILE A  24
 None
 0.74A 3ijdB-5e2cA:
undetectable		 3ijdB-5e2cA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5e2c XAA-PRO DIPEPTIDASE
(Mycobacterium
tuberculosis) 		5 / 12 ARG A  31
SER A 125
ILE A  14
ARG A   6
LEU A  10
 None
 1.08A 3iv6C-5e2cA:
undetectable		 3iv6C-5e2cA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5e2c XAA-PRO DIPEPTIDASE
(Mycobacterium
tuberculosis) 		5 / 11 ALA A  87
ARG A  86
GLY A  91
LEU A  44
ALA A  21
 None
 1.16A 3kw2B-5e2cA:
undetectable		 3kw2B-5e2cA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5e2c XAA-PRO DIPEPTIDASE
(Mycobacterium
tuberculosis) 		4 / 6 SER A 125
GLU A 129
VAL A 102
THR A 103
 None
 1.38A 4lnxA-5e2cA:
undetectable		 4lnxA-5e2cA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 5e2c XAA-PRO DIPEPTIDASE
(Mycobacterium
tuberculosis) 		4 / 7 ALA A 109
GLY A  85
ALA A  84
SER A  25
 None
 0.79A 4r1zB-5e2cA:
undetectable		 4r1zB-5e2cA:
15.60