SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_B_TACB1888_1 (ELONGATION FACTOR EF-TU)	5e2w	AT8 HEAVY CHAIN (Mus musculus)	4 / 5	SER H 28 ASP H 77 PRO H 74 SER H 31	None	1.33A	2hdnA-5e2wH: undetectable 2hdnB-5e2wH: undetectable 2hdnD-5e2wH: undetectable	2hdnA-5e2wH: 16.67 2hdnB-5e2wH: 18.80 2hdnD-5e2wH: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_D_TACD2888_1 (ELONGATION FACTOR EF-TU)	5e2w	AT8 HEAVY CHAIN (Mus musculus)	4 / 5	SER H 31 SER H 28 ASP H 77 PRO H 74	None	1.37A	2hdnB-5e2wH: undetectable 2hdnC-5e2wH: undetectable 2hdnD-5e2wH: undetectable	2hdnB-5e2wH: 18.80 2hdnC-5e2wH: 16.67 2hdnD-5e2wH: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HUO_A_PNNA302_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	5e2w	AT8 HEAVY CHAIN (Mus musculus)	4 / 6	LEU H 189 GLY H 190 ALA H 125 PRO H 126	None	0.38A	3huoA-5e2wH: undetectable	3huoA-5e2wH: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JTP_A_ASCA802_0 (RRNA N-GLYCOSIDASE)	5e2w	AT8 HEAVY CHAIN (Mus musculus)	4 / 5	TYR H 51 ASN H 61 TYR H 60 ILE H 70	None	1.04A	4jtpA-5e2wH: undetectable	4jtpA-5e2wH: 20.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HDN_B_TACB1888_1","ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU","5e2w","AT8 HEAVY CHAIN","Mus musculus",4,"SER H  28;ASP H  77;PRO H  74;SER H  31","None","1.33A","2hdnA-5e2wH:undetectable;2hdnB-5e2wH:undetectable;2hdnD-5e2wH:undetectable","2hdnA-5e2wH:16.67;2hdnB-5e2wH:18.80;2hdnD-5e2wH:18.80"],["2HDN_D_TACD2888_1","ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU","5e2w","AT8 HEAVY CHAIN","Mus musculus",4,"SER H  31;SER H  28;ASP H  77;PRO H  74","None","1.37A","2hdnB-5e2wH:undetectable;2hdnC-5e2wH:undetectable;2hdnD-5e2wH:undetectable","2hdnB-5e2wH:18.80;2hdnC-5e2wH:16.67;2hdnD-5e2wH:18.80"],["3HUO_A_PNNA302_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","5e2w","AT8 HEAVY CHAIN","Mus musculus",4,"LEU H 189;GLY H 190;ALA H 125;PRO H 126","None","0.38A","3huoA-5e2wH:undetectable","3huoA-5e2wH:22.30"],["4JTP_A_ASCA802_0","RRNA N-GLYCOSIDASE","5e2w","AT8 HEAVY CHAIN","Mus musculus",4,"TYR H  51;ASN H  61;TYR H  60;ILE H  70","None","1.04A","4jtpA-5e2wH:undetectable","4jtpA-5e2wH:20.93"]]