SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 5e32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 HIS A 295
LEU A 300
THR A 283
THR A 301
 None
 1.09A 1am6A-5e32A:
undetectable		 1am6A-5e32A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 5e32 HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 ASP A  77
GLU A 255
TYR A 258
 None
 0.84A 1wsvA-5e32A:
undetectable		 1wsvA-5e32A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 5e32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 ILE A  87
SER A 265
ILE A 260
PHE A 118
 None
 1.11A 2q72A-5e32A:
undetectable		 2q72A-5e32A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 5e32 HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 PRO A  58
GLU A 273
TYR A 274
 None
 0.60A 2zmbA-5e32A:
undetectable		 2zmbA-5e32A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5e32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 THR A 200
ASN A 250
ILE A 194
GLU A 190
 None
 1.21A 5uigA-5e32A:
undetectable		 5uigA-5e32A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5e32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 LEU A 179
PHE A 233
LEU A  71
PHE A 148
 None
 1.09A 5w97C-5e32A:
undetectable
5w97J-5e32A:
undetectable		 5w97C-5e32A:
20.47
5w97J-5e32A:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5e32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 LEU A 179
PHE A 233
LEU A  71
PHE A 148
 None
 1.23A 5x1fC-5e32A:
undetectable
5x1fJ-5e32A:
undetectable		 5x1fC-5e32A:
20.47
5x1fJ-5e32A:
10.21