SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 5e3j RESPONSE REGULATOR
RSTA
(Acinetobacter
baumannii) 		3 / 3 LEU A  61
PRO A  62
ARG A  46
 None
 0.39A 2qd4B-5e3jA:
5.8		 2qd4B-5e3jA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 5e3j RESPONSE REGULATOR
RSTA
(Acinetobacter
baumannii) 		3 / 3 LEU A  61
PRO A  62
ARG A  46
 None
 0.41A 2qd5A-5e3jA:
5.4		 2qd5A-5e3jA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 5e3j RESPONSE REGULATOR
RSTA
(Acinetobacter
baumannii) 		3 / 3 PRO A 111
GLU A  25
TYR A  26
 None
 0.72A 2zmbA-5e3jA:
2.5		 2zmbA-5e3jA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 5e3j RESPONSE REGULATOR
RSTA
(Acinetobacter
baumannii) 		4 / 8 GLY A 100
ALA A 101
ASP A 102
THR A  85
 None
 0.67A 3el0A-5e3jA:
undetectable		 3el0A-5e3jA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 5e3j RESPONSE REGULATOR
RSTA
(Acinetobacter
baumannii) 		4 / 5 ARG A 117
LEU A 114
VAL A 109
ASP A 103
 None
 0.91A 3ufnA-5e3jA:
undetectable
3ufnB-5e3jA:
undetectable		 3ufnA-5e3jA:
24.41
3ufnB-5e3jA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 5e3j RESPONSE REGULATOR
RSTA
(Acinetobacter
baumannii) 		5 / 11 GLY A 100
ALA A 101
ASP A 102
ILE A  47
THR A  85
 None
 1.10A 4l1aA-5e3jA:
undetectable		 4l1aA-5e3jA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 5e3j RESPONSE REGULATOR
RSTA
(Acinetobacter
baumannii) 		4 / 5 LEU A 114
LEU A  19
THR A  85
PRO A  62
 None
 1.00A 6ew0F-5e3jA:
undetectable		 6ew0F-5e3jA:
21.54