SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K39_A_SAMA504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	5e3v	ADENYLOSUCCINATE LYASE (Salmonella enterica)	5 / 12	ASN A 313 SER A 317 LEU A 321 ILE A 261 LEU A 144	None	1.17A	4k39A-5e3vA: undetectable	4k39A-5e3vA: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AJQ_A_DB8A800_2 (SERINE/THREONINE-PRO TEIN KINASE 10)	5e3v	ADENYLOSUCCINATE LYASE (Salmonella enterica)	4 / 4	VAL A 12 ILE A 350 ASN A 345 VAL A 320	None	1.30A	5ajqA-5e3vA: undetectable	5ajqA-5e3vA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_Q_PCFQ202_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 1)	5e3v	ADENYLOSUCCINATE LYASE (Salmonella enterica)	4 / 6	TYR A 357 ILE A 143 ALA A 262 ASP A 272	None	1.11A	6hu9m-5e3vA: 1.6 6hu9q-5e3vA: undetectable	6hu9m-5e3vA: 21.13 6hu9q-5e3vA: 15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6I5Z_D_SAMD401_0 (O-METHYLTRANSFERASE 1)	5e3v	ADENYLOSUCCINATE LYASE (Salmonella enterica)	5 / 11	GLY A 351 GLY A 349 LEU A 316 VAL A 320 ASP A 13	None	1.26A	6i5zD-5e3vA: undetectable	6i5zD-5e3vA: 23.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4K39_A_SAMA504_0","ANAEROBIC SULFATASE-MATURATING ENZYME","5e3v","ADENYLOSUCCINATE LYASE","Salmonella enterica",5,"ASN A 313;SER A 317;LEU A 321;ILE A 261;LEU A 144","None","1.17A","4k39A-5e3vA:undetectable","4k39A-5e3vA:21.55"],["5AJQ_A_DB8A800_2","SERINE\/THREONINE-PROTEIN KINASE 10","5e3v","ADENYLOSUCCINATE LYASE","Salmonella enterica",4,"VAL A  12;ILE A 350;ASN A 345;VAL A 320","None","1.30A","5ajqA-5e3vA:undetectable","5ajqA-5e3vA:23.38"],["6HU9_Q_PCFQ202_0","CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL;CYTOCHROME C OXIDASE SUBUNIT 1","5e3v","ADENYLOSUCCINATE LYASE","Salmonella enterica",4,"TYR A 357;ILE A 143;ALA A 262;ASP A 272","None","1.11A","6hu9m-5e3vA:1.6;6hu9q-5e3vA:undetectable","6hu9m-5e3vA:21.13;6hu9q-5e3vA:15.26"],["6I5Z_D_SAMD401_0","O-METHYLTRANSFERASE 1","5e3v","ADENYLOSUCCINATE LYASE","Salmonella enterica",5,"GLY A 351;GLY A 349;LEU A 316;VAL A 320;ASP A  13","None","1.26A","6i5zD-5e3vA:undetectable","6i5zD-5e3vA:23.15"]]