SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e43'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 SER A  70
LYS A  73
SER A 131
ASN A 133
LYS A 235
GLY A 237
 ACT  A 311 (-3.2A)
None
ACT  A 311 (-3.0A)
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.20A 1ghmA-5e43A:
38.9		 1ghmA-5e43A:
35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		8 / 12 SER A  70
LYS A  73
SER A 131
ASN A 133
GLU A 167
THR A 217
LYS A 235
GLY A 237
 ACT  A 311 (-3.2A)
None
ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.33A 1i2wA-5e43A:
41.6		 1i2wA-5e43A:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A  70
LYS A  73
SER A 131
ASN A 133
GLU A 167
THR A 217
GLY A 237
 ACT  A 311 (-3.2A)
None
ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.2A)
 0.34A 1i2wB-5e43A:
41.6		 1i2wB-5e43A:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 SER A  70
LYS A  73
SER A 131
ASN A 133
GLY A 237
ARG A 221
 ACT  A 311 (-3.2A)
None
ACT  A 311 (-3.0A)
None
ACT  A 311 (-3.2A)
ACT  A 311 (-4.5A)
 1.11A 1i2wB-5e43A:
41.6		 1i2wB-5e43A:
38.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 4 HIS A 113
VAL A 109
THR A 119
LEU A 139
 None
ACT  A 302 ( 4.6A)
None
None
 1.50A 1oq5A-5e43A:
undetectable		 1oq5A-5e43A:
19.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		9 / 12 SER A  70
LYS A  73
SER A 131
ASN A 133
GLU A 167
ASN A 171
THR A 217
LYS A 235
GLY A 237
 ACT  A 311 (-3.2A)
None
ACT  A 311 (-3.0A)
None
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.42A 1ymxA-5e43A:
42.6		 1ymxA-5e43A:
41.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		8 / 12 SER A  70
LYS A  73
SER A 131
ASN A 133
GLU A 167
ASN A 171
LYS A 235
GLY A 237
 ACT  A 311 (-3.2A)
None
ACT  A 311 (-3.0A)
None
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.35A 1ymxB-5e43A:
42.8		 1ymxB-5e43A:
41.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 11 SER A 131
SER A  70
ASP A 219
THR A 238
GLY A 237
 ACT  A 311 (-3.0A)
ACT  A 311 (-3.2A)
None
ACT  A 311 (-3.8A)
ACT  A 311 (-3.2A)
 0.98A 2hmaA-5e43A:
undetectable		 2hmaA-5e43A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 12 LEU A 139
ALA A 136
LEU A 149
LEU A  68
THR A 236
 None
None
None
None
ACT  A 311 (-3.7A)
 1.34A 2oaxB-5e43A:
undetectable		 2oaxB-5e43A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.91A 2v2gA-5e43A:
undetectable
2v2gB-5e43A:
undetectable		 2v2gA-5e43A:
20.32
2v2gB-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.90A 2v2gA-5e43A:
undetectable
2v2gB-5e43A:
undetectable		 2v2gA-5e43A:
20.32
2v2gB-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.91A 2v2gC-5e43A:
undetectable
2v2gD-5e43A:
undetectable		 2v2gC-5e43A:
20.32
2v2gD-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.92A 2v2gC-5e43A:
undetectable
2v2gD-5e43A:
undetectable		 2v2gC-5e43A:
20.32
2v2gD-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 8 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.84A 2v32A-5e43A:
undetectable
2v32B-5e43A:
undetectable		 2v32A-5e43A:
20.32
2v32B-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 8 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.87A 2v32A-5e43A:
undetectable
2v32B-5e43A:
undetectable		 2v32A-5e43A:
20.32
2v32B-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 8 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.87A 2v32C-5e43A:
undetectable
2v32D-5e43A:
undetectable		 2v32C-5e43A:
20.32
2v32D-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 8 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.90A 2v32C-5e43A:
undetectable
2v32D-5e43A:
undetectable		 2v32C-5e43A:
20.32
2v32D-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 8 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.88A 2v41C-5e43A:
undetectable
2v41D-5e43A:
undetectable		 2v41C-5e43A:
20.32
2v41D-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 8 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.95A 2v41C-5e43A:
undetectable
2v41D-5e43A:
undetectable		 2v41C-5e43A:
20.32
2v41D-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.84A 2v41E-5e43A:
undetectable
2v41F-5e43A:
undetectable		 2v41E-5e43A:
20.32
2v41F-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.82A 2v41E-5e43A:
undetectable
2v41F-5e43A:
undetectable		 2v41E-5e43A:
20.32
2v41F-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 8 THR A 183
PRO A 184
SER A 186
ARG A 189
 ACT  A 307 (-3.1A)
None
ACT  A 307 (-3.1A)
ACT  A 307 (-3.4A)
 0.87A 2v41G-5e43A:
undetectable
2v41H-5e43A:
undetectable		 2v41G-5e43A:
20.32
2v41H-5e43A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 9 PRO A 146
LEU A 163
LEU A 140
ALA A 136
PHE A  72
 None
 1.05A 2vcvD-5e43A:
undetectable		 2vcvD-5e43A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 9 PRO A 146
LEU A 163
LEU A 140
ALA A 136
PHE A  72
 None
 1.02A 2vcvE-5e43A:
undetectable		 2vcvE-5e43A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 9 PRO A 146
LEU A 163
LEU A 140
ALA A 136
PHE A  72
 None
 1.01A 2vcvH-5e43A:
undetectable		 2vcvH-5e43A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 TYR A 265
PHE A 153
ILE A 248
ASN A 246
 None
 1.23A 2zseA-5e43A:
undetectable		 2zseA-5e43A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 6 ILE A 286
THR A 266
PHE A  66
TYR A  60
 None
 1.10A 3elzB-5e43A:
undetectable		 3elzB-5e43A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 5 ILE A 286
THR A 266
PHE A  66
TYR A  60
 None
 1.05A 3em0A-5e43A:
1.2		 3em0A-5e43A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 VAL A 120
ALA A  77
ALA A  79
LEU A 149
ALA A  74
VAL A  96
 None
 1.41A 3fc6C-5e43A:
undetectable		 3fc6C-5e43A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 10 ALA A  79
VAL A 194
ALA A 127
ILE A 128
LEU A 212
 None
 0.87A 3fl9A-5e43A:
undetectable		 3fl9A-5e43A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 10 ALA A  79
VAL A 194
ALA A 127
ILE A 128
LEU A 212
 None
 0.78A 3fl9F-5e43A:
undetectable		 3fl9F-5e43A:
17.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 LYS A  73
SER A 131
ASN A 133
ASN A 171
THR A 217
LYS A 235
GLY A 237
 None
ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.38A 3hlwA-5e43A:
42.9		 3hlwA-5e43A:
41.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A 131
ASN A 133
ASN A 171
THR A 217
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.31A 3hlwB-5e43A:
42.9		 3hlwB-5e43A:
41.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 LYS A  73
ASN A 133
ASN A 171
LYS A 235
THR A 236
GLY A 237
 None
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.25A 3huoA-5e43A:
42.7		 3huoA-5e43A:
41.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 6 THR A  52
ARG A 192
GLY A 197
ALA A 258
PRO A 259
 None
 0.72A 3huoA-5e43A:
42.7		 3huoA-5e43A:
41.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 12 LYS A  73
ASN A 133
ASN A 171
LYS A 235
GLY A 237
 None
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.24A 3huoB-5e43A:
42.5		 3huoB-5e43A:
41.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 SER A  70
LYS A  73
ASN A 133
THR A 236
GLY A 237
ARG A 221
 ACT  A 311 (-3.2A)
None
None
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-4.5A)
 0.75A 3mzeA-5e43A:
21.7		 3mzeA-5e43A:
21.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		9 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
ARG A 221
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-4.5A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.55A 3ny4A-5e43A:
40.2		 3ny4A-5e43A:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 LYS A  73
SER A 131
ASN A 133
ASN A 171
LYS A 235
GLY A 237
 None
ACT  A 311 (-3.0A)
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.27A 3q07A-5e43A:
42.8		 3q07A-5e43A:
41.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 LYS A  73
SER A 131
ASN A 133
ASN A 171
LYS A 235
GLY A 237
 None
ACT  A 311 (-3.0A)
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.35A 3q07B-5e43A:
42.7		 3q07B-5e43A:
41.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 SER A  70
SER A 131
ASN A 133
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.19A 3sh8A-5e43A:
40.2		 3sh8A-5e43A:
37.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 SER A  70
LYS A  73
SER A 131
ASN A 133
LYS A 235
GLY A 237
 ACT  A 311 (-3.2A)
None
ACT  A 311 (-3.0A)
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.24A 3sh8B-5e43A:
40.1		 3sh8B-5e43A:
37.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 5 TRP A 166
GLY A 144
ALA A 147
PHE A  72
 NO3  A 309 (-4.9A)
NO3  A 309 (-3.4A)
None
None
 1.20A 3wqwA-5e43A:
undetectable		 3wqwA-5e43A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 12 TRP A 230
LEU A 226
LEU A 287
ILE A 260
ILE A 222
 None
 1.26A 4a79A-5e43A:
undetectable		 4a79A-5e43A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 12 TRP A 230
LEU A 226
LEU A 287
ILE A 260
ILE A 222
 None
 1.23A 4a79B-5e43A:
undetectable		 4a79B-5e43A:
21.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		10 / 12 LYS A  73
HIS A 106
SER A 131
ASN A 133
ASN A 171
THR A 217
LYS A 235
THR A 236
GLY A 237
THR A 238
 None
ACT  A 303 (-4.0A)
ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.32A 4euzA-5e43A:
43.5		 4euzA-5e43A:
42.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 10 SER A 131
ASN A 133
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.0A)
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.50A 4fh2A-5e43A:
35.7		 4fh2A-5e43A:
38.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 VAL A  80
ILE A 143
LEU A 170
LEU A 163
 None
 0.98A 4l1wA-5e43A:
undetectable		 4l1wA-5e43A:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A  70
SER A 131
ASN A 133
ASN A 171
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.26A 4n9kA-5e43A:
42.0		 4n9kA-5e43A:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A  70
SER A 131
ASN A 133
ASN A 171
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.27A 4n9kB-5e43A:
42.0		 4n9kB-5e43A:
37.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		5 / 12 TYR A 265
ARG A  44
ASN A 246
ALA A 244
GLY A 245
 None
NO3  A 301 ( 3.6A)
None
None
None
 1.34A 4oadA-5e43A:
undetectable		 4oadA-5e43A:
19.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A 131
ASN A 133
ASN A 171
THR A 217
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.59A 4pm5A-5e43A:
42.7		 4pm5A-5e43A:
41.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 LYS A  73
SER A 131
ASN A 133
ASN A 171
THR A 217
LYS A 235
GLY A 237
 None
ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.64A 4pm7A-5e43A:
42.7		 4pm7A-5e43A:
41.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A 131
ASN A 133
ASN A 171
THR A 217
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.59A 4pm9A-5e43A:
42.5		 4pm9A-5e43A:
43.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 ASP A 247
ILE A 222
GLY A 233
THR A 236
 None
None
None
ACT  A 311 (-3.7A)
 1.14A 4zxiA-5e43A:
undetectable		 4zxiA-5e43A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		3 / 3 ASP A 234
ASN A 246
PHE A  72
 None
 0.73A 5dsgB-5e43A:
undetectable		 5dsgB-5e43A:
23.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 SER A  70
SER A 131
ASN A 133
ASN A 171
LYS A 235
GLY A 237
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.33A 5ghyA-5e43A:
41.9		 5ghyA-5e43A:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 SER A  70
SER A 131
ASN A 133
ASN A 171
LYS A 235
GLY A 237
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.31A 5ghyB-5e43A:
42.0		 5ghyB-5e43A:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 11 SER A  70
SER A 131
ASN A 133
ASN A 171
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.26A 5ghzA-5e43A:
42.0		 5ghzA-5e43A:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 10 SER A  70
SER A 131
ASN A 133
ASN A 171
LYS A 235
THR A 236
GLY A 237
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
 0.26A 5ghzB-5e43A:
42.0		 5ghzB-5e43A:
37.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		4 / 7 THR A 150
PHE A  72
ASP A 180
LEU A 170
 None
 1.20A 5uxcA-5e43A:
undetectable		 5uxcA-5e43A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		9 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
ARG A 221
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-4.5A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.39A 6b5yB-5e43A:
41.1		 6b5yB-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		8 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.45A 6b5yD-5e43A:
41.2		 6b5yD-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		8 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.26A 6b68B-5e43A:
41.3		 6b68B-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		8 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
ARG A 221
LYS A 235
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-4.5A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.35A 6b68D-5e43A:
41.1		 6b68D-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		8 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.28A 6b69A-5e43A:
41.0
6b69B-5e43A:
41.1		 6b69A-5e43A:
15.11
6b69B-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		9 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
ARG A 221
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-4.5A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.30A 6b69D-5e43A:
41.0		 6b69D-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		9 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
ARG A 221
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-4.5A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.34A 6b6aB-5e43A:
41.3		 6b6aB-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		8 / 12 SER A  70
SER A 131
ASN A 171
ARG A 221
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 (-4.5A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.31A 6b6aD-5e43A:
41.2		 6b6aD-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		8 / 12 SER A  70
SER A 131
ASN A 171
ARG A 221
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 (-4.5A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.38A 6b6cA-5e43A:
40.8		 6b6cA-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A  70
ASN A 171
THR A 217
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.31A 6b6dA-5e43A:
40.4		 6b6dA-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A  70
SER A 131
THR A 217
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.53A 6b6dA-5e43A:
40.4		 6b6dA-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		9 / 12 SER A  70
SER A 131
ASN A 171
THR A 217
ARG A 221
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-4.5A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.38A 6b6eA-5e43A:
40.8		 6b6eA-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		7 / 12 SER A  70
SER A 131
ASN A 171
LYS A 235
THR A 236
GLY A 237
THR A 238
 ACT  A 311 (-3.2A)
ACT  A 311 (-3.0A)
None
ACT  A 311 (-3.3A)
ACT  A 311 (-3.7A)
ACT  A 311 (-3.2A)
ACT  A 311 (-3.8A)
 0.44A 6b6fA-5e43A:
40.4		 6b6fA-5e43A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 5e43 BETA-LACTAMASE
(Streptosporangiu
m
roseum) 		6 / 12 SER A 131
ASN A 133
ASN A 171
THR A 217
LYS A 235
GLY A 237
 ACT  A 311 (-3.0A)
None
None
ACT  A 311 ( 3.9A)
ACT  A 311 (-3.3A)
ACT  A 311 (-3.2A)
 0.25A 6c79A-5e43A:
42.6		 6c79A-5e43A:
22.29