SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		4 / 8 ASP A 207
THR A  51
HIS A  14
ILE A  17
 None
 0.84A 1ei6C-5e4vA:
undetectable		 1ei6C-5e4vA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 11 LEU A 345
VAL A 320
GLY A 257
LEU A 267
TYR A 342
 None
 1.30A 1lwcA-5e4vA:
undetectable		 1lwcA-5e4vA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 LEU A  33
LEU A  36
LEU A  50
LEU A  58
ILE A 151
 None
 0.86A 1s9pA-5e4vA:
undetectable		 1s9pA-5e4vA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 LEU A  33
LEU A  36
LEU A  50
LEU A  58
ILE A 151
 None
 1.07A 1s9pD-5e4vA:
undetectable		 1s9pD-5e4vA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 LEU A  33
LEU A 148
ILE A 151
ILE A 155
LEU A  58
 None
 0.86A 2bdmA-5e4vA:
0.8		 2bdmA-5e4vA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		4 / 6 LEU A  33
LEU A 148
PRO A  65
VAL A  62
 None
 1.09A 2dqyC-5e4vA:
0.7		 2dqyC-5e4vA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 10 LEU A 345
VAL A 320
GLY A 257
LEU A 267
TYR A 342
 None
 1.29A 2hnyA-5e4vA:
undetectable		 2hnyA-5e4vA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 LEU A  60
LEU A  32
SER A  64
PRO A  65
GLY A  66
 None
 0.93A 2vmyB-5e4vA:
undetectable		 2vmyB-5e4vA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 LEU A  60
LEU A  32
SER A  64
PRO A  65
GLY A  66
 None
 0.98A 2vmyA-5e4vA:
undetectable		 2vmyA-5e4vA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		4 / 8 TRP A 127
ARG A  38
ASP A  34
ILE A 136
 None
 1.05A 2xadA-5e4vA:
undetectable		 2xadA-5e4vA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		4 / 8 TRP A 127
ARG A  38
ASP A  34
ILE A 136
 None
 1.06A 2xadB-5e4vA:
undetectable		 2xadB-5e4vA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		4 / 8 TRP A 127
ARG A  38
ASP A  34
ILE A 136
 None
 1.08A 2xadC-5e4vA:
undetectable		 2xadC-5e4vA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		4 / 8 TRP A 127
ARG A  38
ASP A  34
ILE A 136
 None
 1.06A 2xadD-5e4vA:
undetectable		 2xadD-5e4vA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 THR A  51
ILE A  16
GLY A  52
GLY A  47
HIS A  14
 None
 1.32A 2y7kC-5e4vA:
undetectable		 2y7kC-5e4vA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 11 ILE A  57
LEU A  33
ILE A 136
THR A 150
LEU A 192
 None
 1.26A 3a51A-5e4vA:
undetectable		 3a51A-5e4vA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 GLY A 257
ALA A 271
GLY A 272
LEU A 277
ILE A 258
 None
 0.90A 3ku1A-5e4vA:
undetectable		 3ku1A-5e4vA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP0_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 9 LEU A 345
VAL A 320
GLY A 257
LEU A 267
TYR A 342
 None
 1.26A 3lp0A-5e4vA:
undetectable		 3lp0A-5e4vA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 10 LEU A 345
VAL A 320
GLY A 257
LEU A 267
TYR A 342
 None
 1.28A 3qipA-5e4vA:
undetectable		 3qipA-5e4vA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 ARG A 389
THR A 260
GLY A 321
GLY A 257
GLY A 319
 None
 1.09A 3tegA-5e4vA:
undetectable		 3tegA-5e4vA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 LEU A 277
LEU A 280
LEU A 283
MET A 294
VAL A 295
 None
 0.86A 3zqtA-5e4vA:
undetectable		 3zqtA-5e4vA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 GLY A 319
ALA A 317
PHE A 333
LEU A 324
VAL A 322
 None
 1.22A 4azsA-5e4vA:
undetectable		 4azsA-5e4vA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 GLY A 319
ALA A 317
PHE A 333
LEU A 324
VAL A 322
 None
 1.23A 4azwA-5e4vA:
undetectable		 4azwA-5e4vA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 LEU A  54
LEU A  50
LEU A  39
ILE A 155
ILE A 151
 None
 1.04A 4j24A-5e4vA:
undetectable		 4j24A-5e4vA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 12 LEU A  54
LEU A  50
LEU A  39
ILE A 155
ILE A 151
 None
 1.09A 4j24B-5e4vA:
undetectable		 4j24B-5e4vA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		4 / 7 LYS A 386
GLN A 347
VAL A 322
GLU A 323
 None
 1.35A 4mv7A-5e4vA:
undetectable		 4mv7A-5e4vA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		3 / 3 ASP A  77
ARG A 203
ARG A 211
 None
 0.99A 5eajB-5e4vA:
undetectable		 5eajB-5e4vA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		4 / 6 GLU A 173
ARG A 176
LEU A 174
TYR A 241
 None
 1.12A 5phhA-5e4vA:
undetectable		 5phhA-5e4vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN
(Measles
morbillivirus) 		5 / 11 PHE A 112
LEU A  95
LEU A  39
PRO A  19
ILE A  17
 None
 1.05A 6fgcA-5e4vA:
undetectable		 6fgcA-5e4vA:
11.19