SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e4w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 5e4w SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ALA C 270
VAL C 272
TRP C 291
 None
 0.89A 1nt6A-5e4wC:
undetectable		 1nt6A-5e4wC:
10.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5e4w SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ARG C 329
LEU C 340
TRP C 343
THR C 350
TRP C 351
 None
 0.36A 4x3uA-5e4wC:
6.4		 4x3uA-5e4wC:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_2
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5e4w SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 ARG C 329
LEU C 340
TRP C 343
THR C 350
TRP C 351
 None
 0.34A 4x3uB-5e4wC:
6.1		 4x3uB-5e4wC:
38.03