SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e53'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 5e53 CONTACTIN-1
(Gallus
gallus) 		5 / 12 ILE A 660
ALA A 643
LEU A 613
THR A 692
ILE A 606
 None
 1.10A 1dyiB-5e53A:
undetectable		 1dyiB-5e53A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5e53 CONTACTIN-1
(Gallus
gallus) 		4 / 6 PRO A 739
GLU A 742
PHE A 737
ARG A 746
 None
 1.44A 1oniA-5e53A:
undetectable
1oniC-5e53A:
undetectable		 1oniA-5e53A:
20.20
1oniC-5e53A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5e53 CONTACTIN-1
(Gallus
gallus) 		5 / 11 ILE A 833
THR A 857
VAL A 818
ILE A 816
ASN A 861
 None
 1.25A 3kpcA-5e53A:
undetectable		 3kpcA-5e53A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 5e53 CONTACTIN-1
(Gallus
gallus) 		4 / 5 GLY A 728
TYR A 725
TYR A 727
GLU A 724
 None
 1.06A 4ae1B-5e53A:
undetectable		 4ae1B-5e53A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5e53 CONTACTIN-1
(Gallus
gallus) 		5 / 12 ALA A 878
GLN A 853
GLY A 830
SER A 851
TYR A 831
 None
 1.34A 5hfjB-5e53A:
undetectable		 5hfjB-5e53A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)		 5e53 CONTACTIN-1
(Gallus
gallus) 		5 / 9 VAL A 659
PHE A 670
THR A 634
ILE A 690
THR A 692
 None
 1.27A 5zsfA-5e53A:
undetectable
5zsfB-5e53A:
undetectable		 5zsfA-5e53A:
12.50
5zsfB-5e53A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 5e53 CONTACTIN-1
(Gallus
gallus) 		4 / 6 LYS A 761
ARG A 712
GLU A 713
ALA A 795
 None
 1.16A 6an0A-5e53A:
undetectable		 6an0A-5e53A:
20.83