SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e55'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIV_A_T3A933_1
(ANDROGEN RECEPTOR)		 5e55 CONTACTIN-6
(Mus
musculus) 		5 / 9 PRO A 704
ILE A 724
GLY A 733
GLU A 784
TYR A 781
 None
 1.50A 2pivA-5e55A:
undetectable		 2pivA-5e55A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5e55 CONTACTIN-6
(Mus
musculus) 		4 / 6 THR A 873
TYR A 842
ASP A 845
THR A 897
 None
 1.05A 3q70A-5e55A:
undetectable		 3q70A-5e55A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5e55 CONTACTIN-6
(Mus
musculus) 		5 / 11 ILE A 633
ALA A 647
SER A 610
ILE A 609
LEU A 616
 None
 1.21A 3qg2B-5e55A:
undetectable		 3qg2B-5e55A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5e55 CONTACTIN-6
(Mus
musculus) 		4 / 8 GLU A 766
ILE A 719
VAL A 738
PHE A 740
 None
 1.02A 4dx7B-5e55A:
undetectable		 4dx7B-5e55A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5e55 CONTACTIN-6
(Mus
musculus) 		4 / 5 ILE A 724
PRO A 725
TYR A 671
VAL A 669
 None
 1.33A 4s0vA-5e55A:
undetectable		 4s0vA-5e55A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5e55 CONTACTIN-6
(Mus
musculus) 		3 / 3 ARG A 856
LYS A 854
GLU A 839
 None
 0.82A 5d0yA-5e55A:
undetectable		 5d0yA-5e55A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5e55 CONTACTIN-6
(Mus
musculus) 		3 / 3 ASN A 883
PRO A 802
GLN A 803
 None
 0.92A 6jnhA-5e55A:
undetectable		 6jnhA-5e55A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5e55 CONTACTIN-6
(Mus
musculus) 		3 / 3 ASN A 883
PRO A 802
GLN A 803
 None
 0.92A 6jogA-5e55A:
undetectable		 6jogA-5e55A:
18.41