SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 TYR A 117
GLY A  46
GLY A  44
ALA A  42
VAL A 139
 None
 1.09A 2zulA-5e5dA:
undetectable		 2zulA-5e5dA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		4 / 5 TYR A  69
ARG A 137
ILE A 109
TYR A 151
 None
 1.12A 3dgqA-5e5dA:
undetectable		 3dgqA-5e5dA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 TYR A 117
GLY A  46
GLY A  44
ALA A  42
VAL A 139
 None
 1.12A 3dmhA-5e5dA:
undetectable		 3dmhA-5e5dA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 ARG A 129
ALA A 131
ILE A  85
ALA A  83
PRO A 126
 None
 0.98A 3jb1A-5e5dA:
undetectable		 3jb1A-5e5dA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 PHE A  63
PHE A 134
TRP A  96
GLY A  62
ILE A 109
 None
 1.41A 3ld6A-5e5dA:
undetectable		 3ld6A-5e5dA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		4 / 8 ARG A 129
ALA A  79
ASP A 123
SER A 125
 None
 1.00A 3qj7A-5e5dA:
undetectable
3qj7D-5e5dA:
undetectable		 3qj7A-5e5dA:
23.71
3qj7D-5e5dA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		4 / 7 ILE A 127
TYR A 117
PHE A  61
ARG A 129
 None
 1.32A 4o7gA-5e5dA:
undetectable
4o7gB-5e5dA:
undetectable		 4o7gA-5e5dA:
24.90
4o7gB-5e5dA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 7 GLU A 142
ARG A  68
TYR A  69
GLY A  44
GLY A  46
 CD  A 202 ( 4.2A)
None
None
None
None
 1.44A 4rdxA-5e5dA:
undetectable		 4rdxA-5e5dA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		4 / 5 HIS A 135
VAL A 139
LEU A  80
THR A  78
 None
 1.35A 5ohhA-5e5dA:
undetectable		 5ohhA-5e5dA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		3 / 3 GLU A 142
HIS A 141
ARG A 137
 CD  A 202 ( 4.2A)
CD  A 202 (-3.4A)
None
 0.98A 5uunA-5e5dA:
undetectable		 5uunA-5e5dA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 5e5d PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		4 / 4 MET A  39
GLY A  40
HIS A  43
GLY A  44
 None
 1.05A 6fgdA-5e5dA:
undetectable		 6fgdA-5e5dA:
19.86