SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e5o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 5e5o I-SMAMI LAGLIDADG
ENDONUCLEASE
(Sordaria
macrospora) 		4 / 4 LEU A 217
SER A 216
TYR A 220
LEU A 221
 None
 1.27A 1xz1A-5e5oA:
undetectable		 1xz1A-5e5oA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 5e5o I-SMAMI LAGLIDADG
ENDONUCLEASE
(Sordaria
macrospora) 		4 / 4 LEU A 217
SER A 216
TYR A 220
LEU A 221
 None
 1.27A 1xz3A-5e5oA:
undetectable		 1xz3A-5e5oA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 5e5o I-SMAMI LAGLIDADG
ENDONUCLEASE
(Sordaria
macrospora) 		5 / 12 LEU A 213
VAL A 176
GLY A 180
LEU A 172
SER A 216
 None
 1.28A 2bxeB-5e5oA:
undetectable		 2bxeB-5e5oA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5e5o I-SMAMI LAGLIDADG
ENDONUCLEASE
(Sordaria
macrospora) 		3 / 3 LEU A  99
TRP A 171
GLY A 174
 None
 0.82A 3l35B-5e5oA:
undetectable
3l35K-5e5oA:
undetectable		 3l35B-5e5oA:
9.86
3l35K-5e5oA:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5e5o I-SMAMI LAGLIDADG
ENDONUCLEASE
(Sordaria
macrospora) 		4 / 5 GLY A 174
TRP A 171
ALA A  12
PHE A  94
 None
 1.34A 3wqwA-5e5oA:
undetectable		 3wqwA-5e5oA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 5e5o I-SMAMI LAGLIDADG
ENDONUCLEASE
(Sordaria
macrospora) 		5 / 12 LEU A 213
VAL A 176
GLY A 180
LEU A 172
SER A 216
 None
 1.38A 4ot2A-5e5oA:
2.3		 4ot2A-5e5oA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5e5o I-SMAMI LAGLIDADG
ENDONUCLEASE
(Sordaria
macrospora) 		5 / 11 PHE A  62
PHE A  61
GLY A  15
ASN A   9
ILE A 100
 None
 1.36A 4zvmA-5e5oA:
undetectable
4zvmB-5e5oA:
undetectable		 4zvmA-5e5oA:
21.38
4zvmB-5e5oA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5e5o I-SMAMI LAGLIDADG
ENDONUCLEASE
(Sordaria
macrospora) 		4 / 7 ILE A 185
LEU A 186
LEU A 200
MET A 297
 None
 0.70A 6g9bA-5e5oA:
undetectable
6g9bB-5e5oA:
undetectable		 6g9bA-5e5oA:
12.75
6g9bB-5e5oA:
12.83