SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e5r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5e5r CONTACTIN-3
(Mus
musculus) 		5 / 12 LEU B 282
ILE B 273
PHE B 269
ASP B 265
GLY B 266
 None
 1.15A 1zz1B-5e5rB:
undetectable
1zz1C-5e5rB:
undetectable		 1zz1B-5e5rB:
18.97
1zz1C-5e5rB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5e5r CONTACTIN-3
(Mus
musculus) 		4 / 5 ARG B 262
ARG B 263
GLY B 266
ASP B 265
 None
 1.33A 6dwjB-5e5rB:
undetectable
6dwjD-5e5rB:
undetectable		 6dwjB-5e5rB:
16.23
6dwjD-5e5rB:
16.23