SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e6t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 5e6t CAPSID
(Norwalk
virus) 		3 / 3 GLU A 394
GLY A 271
THR A 272
 None
 0.58A 3iazA-5e6tA:
undetectable		 3iazA-5e6tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 5e6t CAPSID
(Norwalk
virus) 		3 / 3 GLN A 259
PHE A 395
TYR A 386
 None
 1.01A 3ucjA-5e6tA:
undetectable		 3ucjA-5e6tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5e6t CAPSID
(Norwalk
virus) 		5 / 12 PRO A 349
PHE A 316
PRO A 317
LEU A 369
SER A 320
 None
 1.36A 4a83A-5e6tA:
undetectable		 4a83A-5e6tA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5e6t CAPSID
(Norwalk
virus) 		5 / 12 PRO A 349
PHE A 316
PRO A 317
LEU A 369
SER A 320
 None
 1.35A 4a84A-5e6tA:
undetectable		 4a84A-5e6tA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5e6t CAPSID
(Norwalk
virus) 		4 / 7 LEU A 265
ARG A 262
PRO A 402
VAL A 399
 None
 1.04A 4klrA-5e6tA:
undetectable		 4klrA-5e6tA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 5e6t CAPSID
(Norwalk
virus) 		5 / 11 LEU A 474
VAL A 231
LEU A 234
LEU A 409
LEU A 430
 None
 1.19A 4or0B-5e6tA:
undetectable		 4or0B-5e6tA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5e6t CAPSID
(Norwalk
virus) 		5 / 12 MET A 246
LEU A 486
VAL A 476
LEU A 430
PHE A 492
 None
 1.23A 6b54A-5e6tA:
undetectable		 6b54A-5e6tA:
21.15