SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQH_A_FLPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	VAL A 129 LEU A 103 ILE A 111 GLY A 76 ALA A 75 LEU A 71	None	1.44A	1eqhA-5e72A: undetectable	1eqhA-5e72A: 19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQH_B_FLPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	VAL A 129 LEU A 103 ILE A 111 GLY A 76 ALA A 75 LEU A 71	None	1.46A	1eqhB-5e72A: undetectable	1eqhB-5e72A: 19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_0 (SUN PROTEIN)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	GLY A 191 GLY A 192 ILE A 209 ASP A 235 PRO A 256	None SAM A 400 (-3.7A) SAM A 400 (-3.9A) SAM A 400 (-3.4A) SAM A 400 (-4.2A)	0.63A	1sqfA-5e72A: 14.8	1sqfA-5e72A: 24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXM_A_IMNA2002_1 (SERUM ALBUMIN)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 11	ILE A 291 PHE A 297 ARG A 313 GLY A 299 LYS A 300	None	1.35A	2bxmA-5e72A: undetectable	2bxmA-5e72A: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DPM_A_SAMA300_0 (PROTEIN (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 1))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	PHE A 187 GLY A 189 GLY A 191 ASP A 235 PRO A 256	SAM A 400 (-4.7A) SAM A 400 (-3.3A) None SAM A 400 (-3.4A) SAM A 400 (-4.2A)	1.07A	2dpmA-5e72A: 11.3	2dpmA-5e72A: 23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZM_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	LEU A 165 PHE A 187 GLY A 189 ILE A 209 ASP A 235	None SAM A 400 (-4.7A) SAM A 400 (-3.3A) SAM A 400 (-3.9A) SAM A 400 (-3.4A)	0.87A	2zzmA-5e72A: 16.8	2zzmA-5e72A: 23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZN_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	LEU A 165 PHE A 187 GLY A 189 ILE A 209 ASP A 235	None SAM A 400 (-4.7A) SAM A 400 (-3.3A) SAM A 400 (-3.9A) SAM A 400 (-3.4A)	0.88A	2zznA-5e72A: 16.6	2zznA-5e72A: 23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZN_B_SAMB402_0 (UNCHARACTERIZED PROTEIN MJ0883)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	LEU A 165 PHE A 187 GLY A 189 ILE A 209 ASP A 235	None SAM A 400 (-4.7A) SAM A 400 (-3.3A) SAM A 400 (-3.9A) SAM A 400 (-3.4A)	1.08A	2zznB-5e72A: 15.9	2zznB-5e72A: 23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AY0_B_ADNB402_1 (UNCHARACTERIZED PROTEIN MJ0883)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 10	PHE A 187 GLY A 189 ASP A 208 ILE A 209 ASP A 235	SAM A 400 (-4.7A) SAM A 400 (-3.3A) SAM A 400 (-2.8A) SAM A 400 (-3.9A) SAM A 400 (-3.4A)	0.48A	3ay0B-5e72A: 16.9	3ay0B-5e72A: 23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM4_A_DR7A100_1 (PROTEASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 11	ARG A 168 GLY A 192 ASP A 185 ILE A 183 GLY A 198 LEU A 199	None SAM A 400 (-3.7A) SAM A 400 (-2.8A) None None None	1.41A	3em4A-5e72A: undetectable	3em4A-5e72A: 13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_E_TRPE1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 7	GLY A 198 VAL A 226 ILE A 183 VAL A 174	None	0.87A	3fi0E-5e72A: undetectable	3fi0E-5e72A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HII_A_PNTA901_0 (AMILORIDE-SENSITIVE AMINE OXIDASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	TYR A 257 THR A 295 TYR A 327 SER A 170 VAL A 169	None None None SAM A 400 ( 4.8A) None	1.28A	3hiiA-5e72A: undetectable	3hiiA-5e72A: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU9_B_SPMB700_1 (POLYAMINE OXIDASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 7	GLU A 91 GLU A 5 TYR A 143 TYR A 130	None	1.16A	3ku9B-5e72A: 3.2	3ku9B-5e72A: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_B_DXCB92_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 5	VAL A 126 VAL A 127 ARG A 128 LYS A 106	None	1.49A	3rv5A-5e72A: undetectable 3rv5B-5e72A: undetectable	3rv5A-5e72A: 13.53 3rv5B-5e72A: 13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TTP_A_017A201_2 (HIV-1 PROTEASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 10	GLY A 198 ALA A 197 GLY A 192 LEU A 184 ILE A 183	None None SAM A 400 (-3.7A) None None	0.94A	3ttpB-5e72A: undetectable	3ttpB-5e72A: 14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V8V_B_SAMB801_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 11	GLY A 189 ASP A 208 ASP A 235 PRO A 256 LEU A 271	SAM A 400 (-3.3A) SAM A 400 (-2.8A) SAM A 400 (-3.4A) SAM A 400 (-4.2A) None	0.70A	3v8vB-5e72A: 17.0	3v8vB-5e72A: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BKJ_B_STIB1000_2 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 5	LEU A 2 TYR A 34 MET A 93 ARG A 51	None	1.34A	4bkjB-5e72A: undetectable	4bkjB-5e72A: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_A_SAMA302_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 4	SER A 164 ASP A 208 MET A 213 ASP A 235	SAM A 400 ( 4.3A) SAM A 400 (-2.8A) SAM A 400 (-4.3A) SAM A 400 (-3.4A)	1.37A	4iv0A-5e72A: 14.2	4iv0A-5e72A: 23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_B_SAMB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	ILE A 163 GLY A 189 ILE A 209 MET A 213 ASP A 235	SAM A 400 ( 4.1A) SAM A 400 (-3.3A) SAM A 400 (-3.9A) SAM A 400 (-4.3A) SAM A 400 (-3.4A)	0.98A	4iv0B-5e72A: 14.5	4iv0B-5e72A: 23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV8_A_SAMA301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	GLY A 189 ASP A 208 ILE A 209 MET A 213 ASP A 235 LEU A 271	SAM A 400 (-3.3A) SAM A 400 (-2.8A) SAM A 400 (-3.9A) SAM A 400 (-4.3A) SAM A 400 (-3.4A) None	0.78A	4iv8A-5e72A: 14.3	4iv8A-5e72A: 23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV8_B_SAMB301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	GLY A 189 ASP A 208 ILE A 209 MET A 213 ASP A 235 LEU A 271	SAM A 400 (-3.3A) SAM A 400 (-2.8A) SAM A 400 (-3.9A) SAM A 400 (-4.3A) SAM A 400 (-3.4A) None	0.81A	4iv8B-5e72A: 14.4	4iv8B-5e72A: 23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 4	ILE A 163 SER A 164 ASP A 208 ASP A 235	SAM A 400 ( 4.1A) SAM A 400 ( 4.3A) SAM A 400 (-2.8A) SAM A 400 (-3.4A)	1.14A	4krhB-5e72A: 14.6	4krhB-5e72A: 22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWZ_A_SAMA301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	ILE A 163 GLY A 189 ILE A 209 MET A 213 LEU A 271	SAM A 400 ( 4.1A) SAM A 400 (-3.3A) SAM A 400 (-3.9A) SAM A 400 (-4.3A) None	0.95A	4mwzA-5e72A: 14.4	4mwzA-5e72A: 24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWZ_B_SAMB301_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 4	SER A 164 ASP A 208 MET A 213 ASP A 235	SAM A 400 ( 4.3A) SAM A 400 (-2.8A) SAM A 400 (-4.3A) SAM A 400 (-3.4A)	1.34A	4mwzB-5e72A: 14.2	4mwzB-5e72A: 24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCL_A_SAMA301_0 (O-METHYLTRANSFERASE FAMILY PROTEIN)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	LEU A 231 GLY A 191 ASP A 254 ALA A 154 ALA A 190	None	1.17A	4pclA-5e72A: 15.8	4pclA-5e72A: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTM_A_SAMA301_0 (DNA ADENINE METHYLASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	PHE A 187 GLY A 189 ALA A 190 ILE A 209 PRO A 256 TYR A 257	SAM A 400 (-4.7A) SAM A 400 (-3.3A) None SAM A 400 (-3.9A) SAM A 400 (-4.2A) None	0.83A	4rtmA-5e72A: 12.4	4rtmA-5e72A: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTP_A_SAMA301_0 (DNA ADENINE METHYLASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	GLY A 189 ALA A 190 ILE A 209 ASP A 254 PRO A 256	SAM A 400 (-3.3A) None SAM A 400 (-3.9A) None SAM A 400 (-4.2A)	0.97A	4rtpA-5e72A: 13.9	4rtpA-5e72A: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTP_A_SAMA301_0 (DNA ADENINE METHYLASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	PHE A 187 GLY A 189 ALA A 190 ILE A 209 PRO A 256	SAM A 400 (-4.7A) SAM A 400 (-3.3A) None SAM A 400 (-3.9A) SAM A 400 (-4.2A)	0.55A	4rtpA-5e72A: 13.9	4rtpA-5e72A: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTR_A_SAMA301_0 (DNA ADENINE METHYLASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 11	PHE A 187 ASP A 208 ILE A 209 ASP A 254 PRO A 256	SAM A 400 (-4.7A) SAM A 400 (-2.8A) SAM A 400 (-3.9A) None SAM A 400 (-4.2A)	0.83A	4rtrA-5e72A: 11.2	4rtrA-5e72A: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTR_A_SAMA301_0 (DNA ADENINE METHYLASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 11	PHE A 187 ASP A 208 ILE A 209 PRO A 256 TYR A 257	SAM A 400 (-4.7A) SAM A 400 (-2.8A) SAM A 400 (-3.9A) SAM A 400 (-4.2A) None	0.66A	4rtrA-5e72A: 11.2	4rtrA-5e72A: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTS_A_SAMA301_0 (DNA ADENINE METHYLASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	PHE A 187 GLY A 189 ASP A 208 ILE A 209 PRO A 256 TYR A 257	SAM A 400 (-4.7A) SAM A 400 (-3.3A) SAM A 400 (-2.8A) SAM A 400 (-3.9A) SAM A 400 (-4.2A) None	0.65A	4rtsA-5e72A: 13.2	4rtsA-5e72A: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ALC_L_TIQL1210_1 (ANTI-TICAGRELOR FAB 72, HEAVY CHAIN ANTI-TICAGRELOR FAB 72, LIGHT CHAIN)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 9	THR A 295 TYR A 257 PRO A 256 ASP A 254 LEU A 173	None None SAM A 400 (-4.2A) None None	1.48A	5alcH-5e72A: 0.0	5alcH-5e72A: 21.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5E72_A_SAMA400_0 (N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	12 / 12	ILE A 163 PHE A 187 GLY A 192 ILE A 193 ILE A 209 ARG A 210 MET A 213 ALA A 236 THR A 253 ASP A 254 PRO A 256 LEU A 271	SAM A 400 ( 4.1A) SAM A 400 (-4.7A) SAM A 400 (-3.7A) SAM A 400 (-3.9A) SAM A 400 (-3.9A) None SAM A 400 (-4.3A) SAM A 400 (-3.5A) SAM A 400 (-4.5A) None SAM A 400 (-4.2A) None	0.00A	5e72A-5e72A: 54.0	5e72A-5e72A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5E72_A_SAMA400_1 (N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 4	ASP A 185 GLY A 189 ASP A 208 ASP A 235	SAM A 400 (-2.8A) SAM A 400 (-3.3A) SAM A 400 (-2.8A) SAM A 400 (-3.4A)	0.01A	5e72A-5e72A: 54.0	5e72A-5e72A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB5_B_010B607_0 (HNL ISOENZYME 5)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 10	ALA A 45 ALA A 41 VAL A 39 LEU A 141 VAL A 4	None	1.43A	5eb5B-5e72A: undetectable	5eb5B-5e72A: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_A_SAMA301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	ASP A 235 ALA A 236 ASP A 254 PRO A 256 PHE A 187 GLY A 189	SAM A 400 (-3.4A) SAM A 400 (-3.5A) None SAM A 400 (-4.2A) SAM A 400 (-4.7A) SAM A 400 (-3.3A)	0.70A	5hfjA-5e72A: 3.0	5hfjA-5e72A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_B_SAMB301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	ALA A 236 ASP A 254 PRO A 256 PHE A 187 GLY A 189	SAM A 400 (-3.5A) None SAM A 400 (-4.2A) SAM A 400 (-4.7A) SAM A 400 (-3.3A)	0.64A	5hfjB-5e72A: 2.5	5hfjB-5e72A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_C_SAMC301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	ASP A 235 ALA A 236 PRO A 256 PHE A 187 GLY A 189	SAM A 400 (-3.4A) SAM A 400 (-3.5A) SAM A 400 (-4.2A) SAM A 400 (-4.7A) SAM A 400 (-3.3A)	0.43A	5hfjC-5e72A: 2.6	5hfjC-5e72A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_D_SAMD301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	ASP A 235 ALA A 236 ASP A 254 PRO A 256 PHE A 187 GLY A 189	SAM A 400 (-3.4A) SAM A 400 (-3.5A) None SAM A 400 (-4.2A) SAM A 400 (-4.7A) SAM A 400 (-3.3A)	0.66A	5hfjD-5e72A: 3.5	5hfjD-5e72A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_E_SAME301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	ASP A 235 ALA A 236 ASP A 254 PHE A 187 GLY A 189	SAM A 400 (-3.4A) SAM A 400 (-3.5A) None SAM A 400 (-4.7A) SAM A 400 (-3.3A)	0.59A	5hfjE-5e72A: 5.6	5hfjE-5e72A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_F_SAMF301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	ASP A 235 ALA A 236 ASP A 254 PRO A 256 PHE A 187 GLY A 189	SAM A 400 (-3.4A) SAM A 400 (-3.5A) None SAM A 400 (-4.2A) SAM A 400 (-4.7A) SAM A 400 (-3.3A)	0.65A	5hfjF-5e72A: 2.7	5hfjF-5e72A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_G_SAMG301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	ALA A 236 ASP A 254 PRO A 256 PHE A 187 GLY A 189	SAM A 400 (-3.5A) None SAM A 400 (-4.2A) SAM A 400 (-4.7A) SAM A 400 (-3.3A)	0.73A	5hfjG-5e72A: 3.1	5hfjG-5e72A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_H_SAMH301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	6 / 12	ASP A 235 ALA A 236 ASP A 254 PRO A 256 PHE A 187 GLY A 189	SAM A 400 (-3.4A) SAM A 400 (-3.5A) None SAM A 400 (-4.2A) SAM A 400 (-4.7A) SAM A 400 (-3.3A)	0.66A	5hfjH-5e72A: 5.5	5hfjH-5e72A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HJI_A_ADNA401_1 (TRNA (GUANINE(37)-N1)-MET HYLTRANSFERASE TRM5A)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 11	PHE A 187 GLY A 189 ILE A 209 ASP A 235 PRO A 256	SAM A 400 (-4.7A) SAM A 400 (-3.3A) SAM A 400 (-3.9A) SAM A 400 (-3.4A) SAM A 400 (-4.2A)	0.65A	5hjiA-5e72A: 3.1	5hjiA-5e72A: 27.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ND2_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	ASP A 33 LEU A 107 ALA A 65 ARG A 128 LEU A 61	None	1.37A	5nd2B-5e72A: 2.2	5nd2B-5e72A: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_A_SAMA501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	GLY A 192 ASP A 208 ASP A 235 ASP A 254 LEU A 271	SAM A 400 (-3.7A) SAM A 400 (-2.8A) SAM A 400 (-3.4A) None None	1.09A	5wwsA-5e72A: 14.3	5wwsA-5e72A: 24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA605_0 (ALPHA-AMYLASE)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	4 / 8	TYR A 229 GLY A 198 ILE A 195 ASP A 185	None None None SAM A 400 (-2.8A)	0.91A	6ag0A-5e72A: undetectable	6ag0A-5e72A: 14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_A_ADNA401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	ASP A 208 ILE A 209 ASP A 235 ALA A 236 LEU A 271	SAM A 400 (-2.8A) SAM A 400 (-3.9A) SAM A 400 (-3.4A) SAM A 400 (-3.5A) None	0.91A	6bq4A-5e72A: 12.9	6bq4A-5e72A: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MHT_D_SAMD328_0 (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI)	5e72	N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE (Thermococcus kodakarensis)	5 / 12	PHE A 187 GLY A 189 GLY A 192 ASP A 235 SER A 164	SAM A 400 (-4.7A) SAM A 400 (-3.3A) SAM A 400 (-3.7A) SAM A 400 (-3.4A) SAM A 400 ( 4.3A)	0.90A	6mhtA-5e72A: 8.8	6mhtA-5e72A: 23.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQH_A_FLPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"VAL A 129;LEU A 103;ILE A 111;GLY A  76;ALA A  75;LEU A  71","None","1.44A","1eqhA-5e72A:undetectable","1eqhA-5e72A:19.66"],["1EQH_B_FLPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"VAL A 129;LEU A 103;ILE A 111;GLY A  76;ALA A  75;LEU A  71","None","1.46A","1eqhB-5e72A:undetectable","1eqhB-5e72A:19.66"],["1SQF_A_SAMA430_0","SUN PROTEIN","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"GLY A 191;GLY A 192;ILE A 209;ASP A 235;PRO A 256","None;SAM A 400 (-3.7A);SAM A 400 (-3.9A);SAM A 400 (-3.4A);SAM A 400 (-4.2A)","0.63A","1sqfA-5e72A:14.8","1sqfA-5e72A:24.94"],["2BXM_A_IMNA2002_1","SERUM ALBUMIN","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ILE A 291;PHE A 297;ARG A 313;GLY A 299;LYS A 300","None","1.35A","2bxmA-5e72A:undetectable","2bxmA-5e72A:19.39"],["2DPM_A_SAMA300_0","PROTEIN (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 1)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"PHE A 187;GLY A 189;GLY A 191;ASP A 235;PRO A 256","SAM A 400 (-4.7A);SAM A 400 (-3.3A);None;SAM A 400 (-3.4A);SAM A 400 (-4.2A)","1.07A","2dpmA-5e72A:11.3","2dpmA-5e72A:23.51"],["2ZZM_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"LEU A 165;PHE A 187;GLY A 189;ILE A 209;ASP A 235","None;SAM A 400 (-4.7A);SAM A 400 (-3.3A);SAM A 400 (-3.9A);SAM A 400 (-3.4A)","0.87A","2zzmA-5e72A:16.8","2zzmA-5e72A:23.47"],["2ZZN_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"LEU A 165;PHE A 187;GLY A 189;ILE A 209;ASP A 235","None;SAM A 400 (-4.7A);SAM A 400 (-3.3A);SAM A 400 (-3.9A);SAM A 400 (-3.4A)","0.88A","2zznA-5e72A:16.6","2zznA-5e72A:23.47"],["2ZZN_B_SAMB402_0","UNCHARACTERIZED PROTEIN MJ0883","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"LEU A 165;PHE A 187;GLY A 189;ILE A 209;ASP A 235","None;SAM A 400 (-4.7A);SAM A 400 (-3.3A);SAM A 400 (-3.9A);SAM A 400 (-3.4A)","1.08A","2zznB-5e72A:15.9","2zznB-5e72A:23.47"],["3AY0_B_ADNB402_1","UNCHARACTERIZED PROTEIN MJ0883","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"PHE A 187;GLY A 189;ASP A 208;ILE A 209;ASP A 235","SAM A 400 (-4.7A);SAM A 400 (-3.3A);SAM A 400 (-2.8A);SAM A 400 (-3.9A);SAM A 400 (-3.4A)","0.48A","3ay0B-5e72A:16.9","3ay0B-5e72A:23.47"],["3EM4_A_DR7A100_1","PROTEASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"ARG A 168;GLY A 192;ASP A 185;ILE A 183;GLY A 198;LEU A 199","None;SAM A 400 (-3.7A);SAM A 400 (-2.8A);None;None;None","1.41A","3em4A-5e72A:undetectable","3em4A-5e72A:13.66"],["3FI0_E_TRPE1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"GLY A 198;VAL A 226;ILE A 183;VAL A 174","None","0.87A","3fi0E-5e72A:undetectable","3fi0E-5e72A:23.56"],["3HII_A_PNTA901_0","AMILORIDE-SENSITIVE AMINE OXIDASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"TYR A 257;THR A 295;TYR A 327;SER A 170;VAL A 169","None;None;None;SAM A 400 ( 4.8A);None","1.28A","3hiiA-5e72A:undetectable","3hiiA-5e72A:20.16"],["3KU9_B_SPMB700_1","POLYAMINE OXIDASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"GLU A  91;GLU A   5;TYR A 143;TYR A 130","None","1.16A","3ku9B-5e72A:3.2","3ku9B-5e72A:21.18"],["3RV5_B_DXCB92_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"VAL A 126;VAL A 127;ARG A 128;LYS A 106","None","1.49A","3rv5A-5e72A:undetectable;3rv5B-5e72A:undetectable","3rv5A-5e72A:13.53;3rv5B-5e72A:13.53"],["3TTP_A_017A201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"GLY A 198;ALA A 197;GLY A 192;LEU A 184;ILE A 183","None;None;SAM A 400 (-3.7A);None;None","0.94A","3ttpB-5e72A:undetectable","3ttpB-5e72A:14.58"],["3V8V_B_SAMB801_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"GLY A 189;ASP A 208;ASP A 235;PRO A 256;LEU A 271","SAM A 400 (-3.3A);SAM A 400 (-2.8A);SAM A 400 (-3.4A);SAM A 400 (-4.2A);None","0.70A","3v8vB-5e72A:17.0","3v8vB-5e72A:19.55"],["4BKJ_B_STIB1000_2","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"LEU A   2;TYR A  34;MET A  93;ARG A  51","None","1.34A","4bkjB-5e72A:undetectable","4bkjB-5e72A:22.10"],["4IV0_A_SAMA302_1","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"SER A 164;ASP A 208;MET A 213;ASP A 235","SAM A 400 ( 4.3A);SAM A 400 (-2.8A);SAM A 400 (-4.3A);SAM A 400 (-3.4A)","1.37A","4iv0A-5e72A:14.2","4iv0A-5e72A:23.31"],["4IV0_B_SAMB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ILE A 163;GLY A 189;ILE A 209;MET A 213;ASP A 235","SAM A 400 ( 4.1A);SAM A 400 (-3.3A);SAM A 400 (-3.9A);SAM A 400 (-4.3A);SAM A 400 (-3.4A)","0.98A","4iv0B-5e72A:14.5","4iv0B-5e72A:23.31"],["4IV8_A_SAMA301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE,PUTATIVE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"GLY A 189;ASP A 208;ILE A 209;MET A 213;ASP A 235;LEU A 271","SAM A 400 (-3.3A);SAM A 400 (-2.8A);SAM A 400 (-3.9A);SAM A 400 (-4.3A);SAM A 400 (-3.4A);None","0.78A","4iv8A-5e72A:14.3","4iv8A-5e72A:23.86"],["4IV8_B_SAMB301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE,PUTATIVE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"GLY A 189;ASP A 208;ILE A 209;MET A 213;ASP A 235;LEU A 271","SAM A 400 (-3.3A);SAM A 400 (-2.8A);SAM A 400 (-3.9A);SAM A 400 (-4.3A);SAM A 400 (-3.4A);None","0.81A","4iv8B-5e72A:14.4","4iv8B-5e72A:23.86"],["4KRH_B_SAMB900_1","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"ILE A 163;SER A 164;ASP A 208;ASP A 235","SAM A 400 ( 4.1A);SAM A 400 ( 4.3A);SAM A 400 (-2.8A);SAM A 400 (-3.4A)","1.14A","4krhB-5e72A:14.6","4krhB-5e72A:22.85"],["4MWZ_A_SAMA301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ILE A 163;GLY A 189;ILE A 209;MET A 213;LEU A 271","SAM A 400 ( 4.1A);SAM A 400 (-3.3A);SAM A 400 (-3.9A);SAM A 400 (-4.3A);None","0.95A","4mwzA-5e72A:14.4","4mwzA-5e72A:24.86"],["4MWZ_B_SAMB301_1","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"SER A 164;ASP A 208;MET A 213;ASP A 235","SAM A 400 ( 4.3A);SAM A 400 (-2.8A);SAM A 400 (-4.3A);SAM A 400 (-3.4A)","1.34A","4mwzB-5e72A:14.2","4mwzB-5e72A:24.86"],["4PCL_A_SAMA301_0","O-METHYLTRANSFERASE FAMILY PROTEIN","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"LEU A 231;GLY A 191;ASP A 254;ALA A 154;ALA A 190","None","1.17A","4pclA-5e72A:15.8","4pclA-5e72A:21.22"],["4RTM_A_SAMA301_0","DNA ADENINE METHYLASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"PHE A 187;GLY A 189;ALA A 190;ILE A 209;PRO A 256;TYR A 257","SAM A 400 (-4.7A);SAM A 400 (-3.3A);None;SAM A 400 (-3.9A);SAM A 400 (-4.2A);None","0.83A","4rtmA-5e72A:12.4","4rtmA-5e72A:23.32"],["4RTP_A_SAMA301_0","DNA ADENINE METHYLASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"GLY A 189;ALA A 190;ILE A 209;ASP A 254;PRO A 256","SAM A 400 (-3.3A);None;SAM A 400 (-3.9A);None;SAM A 400 (-4.2A)","0.97A","4rtpA-5e72A:13.9","4rtpA-5e72A:23.32"],["4RTP_A_SAMA301_0","DNA ADENINE METHYLASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"PHE A 187;GLY A 189;ALA A 190;ILE A 209;PRO A 256","SAM A 400 (-4.7A);SAM A 400 (-3.3A);None;SAM A 400 (-3.9A);SAM A 400 (-4.2A)","0.55A","4rtpA-5e72A:13.9","4rtpA-5e72A:23.32"],["4RTR_A_SAMA301_0","DNA ADENINE METHYLASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"PHE A 187;ASP A 208;ILE A 209;ASP A 254;PRO A 256","SAM A 400 (-4.7A);SAM A 400 (-2.8A);SAM A 400 (-3.9A);None;SAM A 400 (-4.2A)","0.83A","4rtrA-5e72A:11.2","4rtrA-5e72A:23.32"],["4RTR_A_SAMA301_0","DNA ADENINE METHYLASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"PHE A 187;ASP A 208;ILE A 209;PRO A 256;TYR A 257","SAM A 400 (-4.7A);SAM A 400 (-2.8A);SAM A 400 (-3.9A);SAM A 400 (-4.2A);None","0.66A","4rtrA-5e72A:11.2","4rtrA-5e72A:23.32"],["4RTS_A_SAMA301_0","DNA ADENINE METHYLASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"PHE A 187;GLY A 189;ASP A 208;ILE A 209;PRO A 256;TYR A 257","SAM A 400 (-4.7A);SAM A 400 (-3.3A);SAM A 400 (-2.8A);SAM A 400 (-3.9A);SAM A 400 (-4.2A);None","0.65A","4rtsA-5e72A:13.2","4rtsA-5e72A:23.32"],["5ALC_L_TIQL1210_1","ANTI-TICAGRELOR FAB 72, HEAVY CHAIN;ANTI-TICAGRELOR FAB 72, LIGHT CHAIN","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"THR A 295;TYR A 257;PRO A 256;ASP A 254;LEU A 173","None;None;SAM A 400 (-4.2A);None;None","1.48A","5alcH-5e72A:0.0","5alcH-5e72A:21.35"],["5E72_A_SAMA400_0","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",12,"ILE A 163;PHE A 187;GLY A 192;ILE A 193;ILE A 209;ARG A 210;MET A 213;ALA A 236;THR A 253;ASP A 254;PRO A 256;LEU A 271","SAM A 400 ( 4.1A);SAM A 400 (-4.7A);SAM A 400 (-3.7A);SAM A 400 (-3.9A);SAM A 400 (-3.9A);None;SAM A 400 (-4.3A);SAM A 400 (-3.5A);SAM A 400 (-4.5A);None;SAM A 400 (-4.2A);None","0.00A","5e72A-5e72A:54.0","5e72A-5e72A:100.00"],["5E72_A_SAMA400_1","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"ASP A 185;GLY A 189;ASP A 208;ASP A 235","SAM A 400 (-2.8A);SAM A 400 (-3.3A);SAM A 400 (-2.8A);SAM A 400 (-3.4A)","0.01A","5e72A-5e72A:54.0","5e72A-5e72A:100.00"],["5EB5_B_010B607_0","HNL ISOENZYME 5","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ALA A  45;ALA A  41;VAL A  39;LEU A 141;VAL A   4","None","1.43A","5eb5B-5e72A:undetectable","5eb5B-5e72A:21.82"],["5HFJ_A_SAMA301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"ASP A 235;ALA A 236;ASP A 254;PRO A 256;PHE A 187;GLY A 189","SAM A 400 (-3.4A);SAM A 400 (-3.5A);None;SAM A 400 (-4.2A);SAM A 400 (-4.7A);SAM A 400 (-3.3A)","0.70A","5hfjA-5e72A:3.0","5hfjA-5e72A:22.91"],["5HFJ_B_SAMB301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ALA A 236;ASP A 254;PRO A 256;PHE A 187;GLY A 189","SAM A 400 (-3.5A);None;SAM A 400 (-4.2A);SAM A 400 (-4.7A);SAM A 400 (-3.3A)","0.64A","5hfjB-5e72A:2.5","5hfjB-5e72A:22.91"],["5HFJ_C_SAMC301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ASP A 235;ALA A 236;PRO A 256;PHE A 187;GLY A 189","SAM A 400 (-3.4A);SAM A 400 (-3.5A);SAM A 400 (-4.2A);SAM A 400 (-4.7A);SAM A 400 (-3.3A)","0.43A","5hfjC-5e72A:2.6","5hfjC-5e72A:22.91"],["5HFJ_D_SAMD301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"ASP A 235;ALA A 236;ASP A 254;PRO A 256;PHE A 187;GLY A 189","SAM A 400 (-3.4A);SAM A 400 (-3.5A);None;SAM A 400 (-4.2A);SAM A 400 (-4.7A);SAM A 400 (-3.3A)","0.66A","5hfjD-5e72A:3.5","5hfjD-5e72A:22.91"],["5HFJ_E_SAME301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ASP A 235;ALA A 236;ASP A 254;PHE A 187;GLY A 189","SAM A 400 (-3.4A);SAM A 400 (-3.5A);None;SAM A 400 (-4.7A);SAM A 400 (-3.3A)","0.59A","5hfjE-5e72A:5.6","5hfjE-5e72A:22.91"],["5HFJ_F_SAMF301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"ASP A 235;ALA A 236;ASP A 254;PRO A 256;PHE A 187;GLY A 189","SAM A 400 (-3.4A);SAM A 400 (-3.5A);None;SAM A 400 (-4.2A);SAM A 400 (-4.7A);SAM A 400 (-3.3A)","0.65A","5hfjF-5e72A:2.7","5hfjF-5e72A:22.91"],["5HFJ_G_SAMG301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ALA A 236;ASP A 254;PRO A 256;PHE A 187;GLY A 189","SAM A 400 (-3.5A);None;SAM A 400 (-4.2A);SAM A 400 (-4.7A);SAM A 400 (-3.3A)","0.73A","5hfjG-5e72A:3.1","5hfjG-5e72A:22.91"],["5HFJ_H_SAMH301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",6,"ASP A 235;ALA A 236;ASP A 254;PRO A 256;PHE A 187;GLY A 189","SAM A 400 (-3.4A);SAM A 400 (-3.5A);None;SAM A 400 (-4.2A);SAM A 400 (-4.7A);SAM A 400 (-3.3A)","0.66A","5hfjH-5e72A:5.5","5hfjH-5e72A:22.91"],["5HJI_A_ADNA401_1","TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE TRM5A","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"PHE A 187;GLY A 189;ILE A 209;ASP A 235;PRO A 256","SAM A 400 (-4.7A);SAM A 400 (-3.3A);SAM A 400 (-3.9A);SAM A 400 (-3.4A);SAM A 400 (-4.2A)","0.65A","5hjiA-5e72A:3.1","5hjiA-5e72A:27.85"],["5ND2_B_TA1B601_1","TUBULIN BETA-2B CHAIN","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ASP A  33;LEU A 107;ALA A  65;ARG A 128;LEU A  61","None","1.37A","5nd2B-5e72A:2.2","5nd2B-5e72A:23.16"],["5WWS_A_SAMA501_0","PUTATIVE METHYLTRANSFERASE NSUN6","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"GLY A 192;ASP A 208;ASP A 235;ASP A 254;LEU A 271","SAM A 400 (-3.7A);SAM A 400 (-2.8A);SAM A 400 (-3.4A);None;None","1.09A","5wwsA-5e72A:14.3","5wwsA-5e72A:24.44"],["6AG0_A_ACRA605_0","ALPHA-AMYLASE","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",4,"TYR A 229;GLY A 198;ILE A 195;ASP A 185","None;None;None;SAM A 400 (-2.8A)","0.91A","6ag0A-5e72A:undetectable","6ag0A-5e72A:14.75"],["6BQ4_A_ADNA401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"ASP A 208;ILE A 209;ASP A 235;ALA A 236;LEU A 271","SAM A 400 (-2.8A);SAM A 400 (-3.9A);SAM A 400 (-3.4A);SAM A 400 (-3.5A);None","0.91A","6bq4A-5e72A:12.9","6bq4A-5e72A:12.90"],["6MHT_D_SAMD328_0","CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI","5e72","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","Thermococcus kodakarensis",5,"PHE A 187;GLY A 189;GLY A 192;ASP A 235;SER A 164","SAM A 400 (-4.7A);SAM A 400 (-3.3A);SAM A 400 (-3.7A);SAM A 400 (-3.4A);SAM A 400 ( 4.3A)","0.90A","6mhtA-5e72A:8.8","6mhtA-5e72A:23.75"]]