SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		3 / 3 GLU A 445
TYR A 383
PHE A 261
 None
 0.76A 1eqbB-5e76A:
undetectable		 1eqbB-5e76A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		3 / 3 GLU A 445
TYR A 383
PHE A 261
 None
 0.77A 1eqbA-5e76A:
undetectable		 1eqbA-5e76A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		3 / 3 GLU A 445
TYR A 383
PHE A 261
 None
 0.77A 1eqbD-5e76A:
undetectable		 1eqbD-5e76A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		3 / 3 GLU A 445
TYR A 383
PHE A 261
 None
 0.77A 1eqbC-5e76A:
undetectable		 1eqbC-5e76A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		5 / 12 ILE A 213
ALA A 210
ALA A 209
LEU A 189
ALA A 192
 None
 1.07A 1fbyA-5e76A:
undetectable		 1fbyA-5e76A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		5 / 12 ILE A 213
ALA A 210
ALA A 209
LEU A 189
ALA A 192
 None
 1.06A 1fbyB-5e76A:
undetectable		 1fbyB-5e76A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		5 / 11 TYR A 309
ILE A 357
LEU A 289
VAL A  92
ASP A  96
 None
None
None
CL  A 615 (-4.0A)
None
 1.50A 1mrlA-5e76A:
undetectable
1mrlB-5e76A:
undetectable		 1mrlA-5e76A:
17.61
1mrlB-5e76A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		5 / 10 GLU A 270
LEU A 260
ARG A 326
PHE A 442
ALA A 388
 None
 1.11A 1wygA-5e76A:
undetectable		 1wygA-5e76A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		4 / 5 PRO A  85
PRO A  69
ILE A  70
GLY A  73
 None
 1.14A 2jkjD-5e76A:
undetectable		 2jkjD-5e76A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		4 / 5 PRO A  85
PRO A  69
ILE A  70
GLY A  73
 None
 1.14A 2jkjF-5e76A:
undetectable		 2jkjF-5e76A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		4 / 7 PHE A 499
GLY A 502
ASP A 477
TYR A 506
 None
 1.22A 3aruA-5e76A:
undetectable		 3aruA-5e76A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		5 / 11 ILE A 423
ALA A 421
GLY A 443
TYR A 319
GLU A 320
 None
 1.37A 4jdsD-5e76A:
undetectable		 4jdsD-5e76A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		5 / 12 ILE A 161
LEU A 535
ILE A 159
TYR A 148
THR A 111
 EDO  A 610 (-4.8A)
None
EDO  A 610 ( 4.5A)
None
None
 1.11A 4m2xG-5e76A:
undetectable		 4m2xG-5e76A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		4 / 4 CYH A 146
LEU A 273
LEU A 142
ALA A 205
 None
 1.11A 5hpuA-5e76A:
undetectable
5hpuB-5e76A:
undetectable		 5hpuA-5e76A:
3.23
5hpuB-5e76A:
5.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_T_CHDT103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		5 / 10 GLY A  71
THR A 382
ARG A 438
PHE A 442
GLY A 443
 None
 1.33A 5iy5A-5e76A:
0.3
5iy5B-5e76A:
undetectable
5iy5T-5e76A:
undetectable		 5iy5A-5e76A:
21.53
5iy5B-5e76A:
18.56
5iy5T-5e76A:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		3 / 3 SER A 339
TYR A 338
TYR A 337
 None
 0.87A 5lakA-5e76A:
undetectable
5lakI-5e76A:
undetectable		 5lakA-5e76A:
20.93
5lakI-5e76A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		3 / 3 SER A 339
TYR A 338
TYR A 337
 None
 0.85A 5lakC-5e76A:
undetectable
5lakJ-5e76A:
undetectable		 5lakC-5e76A:
20.93
5lakJ-5e76A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		4 / 7 LEU A 214
VAL A 245
GLN A 240
GLU A 236
 None
 1.11A 5tudA-5e76A:
3.7		 5tudA-5e76A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		4 / 5 TYR A 337
TYR A 348
GLY A 347
GLY A 346
 None
 0.96A 5x7pA-5e76A:
undetectable		 5x7pA-5e76A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		4 / 6 TYR A 337
TYR A 348
GLY A 347
GLY A 346
 None
 0.97A 5x7pB-5e76A:
undetectable		 5x7pB-5e76A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		3 / 3 ARG A 420
PHE A 442
ARG A 386
 None
 0.90A 5y9yA-5e76A:
undetectable		 5y9yA-5e76A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 5e76 SUSD-LIKE PROTEIN
BACOVA_02651
(Bacteroides
ovatus) 		5 / 12 ASP A 528
ASP A  96
ASN A  98
PRO A  69
GLY A  73
 EDO  A 610 (-3.2A)
None
None
None
None
 1.46A 6gnfA-5e76A:
undetectable		 6gnfA-5e76A:
21.80