SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		4 / 8 SER A 308
PHE A 312
LEU A 287
LEU A 315
 None
 1.02A 2bfpD-5e7hA:
undetectable		 2bfpD-5e7hA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		5 / 11 HIS A 296
ASN A 317
VAL A 487
ASN A 264
SER A 239
 None
 1.36A 2iyfA-5e7hA:
undetectable		 2iyfA-5e7hA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		4 / 6 GLN A 453
ASN A 457
ASN A 317
LEU A 389
 None
 1.10A 2nyrA-5e7hA:
undetectable		 2nyrA-5e7hA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		5 / 11 THR A 350
VAL A 337
VAL A 318
LEU A 315
ILE A 325
 None
 1.42A 3elzB-5e7hA:
undetectable		 3elzB-5e7hA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		5 / 12 VAL A 248
LEU A 315
SER A 246
THR A 292
PRO A 288
 None
 1.27A 3j6pB-5e7hA:
undetectable		 3j6pB-5e7hA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		4 / 4 ASN A 469
ALA A 475
GLY A 403
THR A 402
 None
 1.31A 4bboC-5e7hA:
undetectable		 4bboC-5e7hA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		4 / 6 SER A 426
SER A 440
ARG A 485
GLU A 394
 None
 1.03A 4eysA-5e7hA:
undetectable		 4eysA-5e7hA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		4 / 4 ILE A 486
LEU A 389
LYS A 390
ASN A 317
 None
 1.06A 4g19D-5e7hA:
undetectable		 4g19D-5e7hA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		5 / 11 HIS A 296
ASN A 317
VAL A 487
ASN A 264
SER A 239
 None
 1.36A 4m83A-5e7hA:
undetectable		 4m83A-5e7hA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		5 / 11 HIS A 296
ASN A 317
VAL A 487
ASN A 264
SER A 239
 None
 1.35A 4m83B-5e7hA:
undetectable		 4m83B-5e7hA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		4 / 4 TYR A 313
GLY A 245
SER A 246
LEU A 287
 None
 1.38A 5bphC-5e7hA:
undetectable		 5bphC-5e7hA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		5 / 12 VAL A 248
LEU A 315
SER A 246
THR A 292
PRO A 288
 None
 1.27A 5hnzB-5e7hA:
undetectable		 5hnzB-5e7hA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		3 / 3 TYR A 466
SER A 368
TRP A 364
 None
 1.03A 5n8jB-5e7hA:
undetectable		 5n8jB-5e7hA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		3 / 3 TYR A 466
SER A 368
TRP A 364
 None
 1.04A 5n8jA-5e7hA:
undetectable		 5n8jA-5e7hA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		3 / 3 TYR A 466
SER A 368
TRP A 364
 None
 1.06A 5n8jD-5e7hA:
undetectable		 5n8jD-5e7hA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650
(Bacteroides
ovatus) 		5 / 12 SER A 370
ILE A 408
TYR A 322
LEU A 391
ALA A 372
 None
 1.36A 5zwrB-5e7hA:
undetectable		 5zwrB-5e7hA:
21.09