SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 835
 None
 0.96A 1av2A-5e7lA:
undetectable
1av2B-5e7lA:
undetectable		 1av2A-5e7lA:
10.67
1av2B-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 TRP A 835
ALA A 819
VAL A 821
 None
 0.88A 1av2C-5e7lA:
undetectable
1av2D-5e7lA:
undetectable		 1av2C-5e7lA:
10.67
1av2D-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 TRP A 835
ALA A 819
VAL A 821
 None
 0.88A 1bdwA-5e7lA:
undetectable
1bdwB-5e7lA:
undetectable		 1bdwA-5e7lA:
10.67
1bdwB-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.78A 1jo3A-5e7lA:
undetectable		 1jo3A-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.77A 1jo3B-5e7lA:
undetectable		 1jo3B-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.92A 1jo4A-5e7lA:
undetectable		 1jo4A-5e7lA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.92A 1jo4B-5e7lA:
undetectable		 1jo4B-5e7lA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.94A 1magA-5e7lA:
undetectable		 1magA-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.94A 1magB-5e7lA:
undetectable		 1magB-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.91A 1ng8A-5e7lA:
undetectable		 1ng8A-5e7lA:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.92A 1ng8B-5e7lA:
undetectable		 1ng8B-5e7lA:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.94A 1nruA-5e7lA:
undetectable		 1nruA-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 ALA A 819
VAL A 821
TRP A 822
 None
 0.94A 1nruB-5e7lA:
undetectable		 1nruB-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 TRP A 835
ALA A 819
VAL A 821
 None
 1.00A 1w5uA-5e7lA:
undetectable
1w5uB-5e7lA:
undetectable		 1w5uA-5e7lA:
10.67
1w5uB-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 TRP A 835
ALA A 819
VAL A 821
 None
 0.98A 2izqC-5e7lA:
undetectable
2izqD-5e7lA:
undetectable		 2izqC-5e7lA:
10.67
2izqD-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 TRP A 835
ALA A 819
VAL A 821
 None
 0.90A 3l8lA-5e7lA:
undetectable
3l8lB-5e7lA:
undetectable		 3l8lA-5e7lA:
10.67
3l8lB-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 5e7l CONTACTIN-2
(Mus
musculus) 		3 / 3 TRP A 835
ALA A 819
VAL A 821
 None
 0.99A 3l8lC-5e7lA:
undetectable
3l8lD-5e7lA:
undetectable		 3l8lC-5e7lA:
10.67
3l8lD-5e7lA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 5e7l CONTACTIN-2
(Mus
musculus) 		5 / 10 PRO A 782
ASN A 894
GLY A 844
GLY A 724
ALA A 810
 None
 1.15A 3pp7B-5e7lA:
undetectable		 3pp7B-5e7lA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 5e7l CONTACTIN-2
(Mus
musculus) 		4 / 7 THR A 784
ARG A 754
SER A 779
HIS A 781
 None
 1.44A 4o4dA-5e7lA:
undetectable		 4o4dA-5e7lA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 5e7l CONTACTIN-2
(Mus
musculus) 		5 / 12 LEU A 719
GLY A 718
ALA A 805
GLY A 721
LEU A 750
 None
 0.66A 5xv7A-5e7lA:
undetectable		 5xv7A-5e7lA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)		 5e7l CONTACTIN-2
(Mus
musculus) 		5 / 9 VAL A 674
PHE A 685
THR A 649
ILE A 705
THR A 707
 None
 1.27A 5zsfA-5e7lA:
undetectable
5zsfB-5e7lA:
undetectable		 5zsfA-5e7lA:
13.27
5zsfB-5e7lA:
13.27